中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
上海生物化学与细胞生... [2]
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OAI收割 [14]
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期刊论文 [14]
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2016 [1]
2009 [5]
2008 [7]
2005 [1]
学科主题
Biochemist... [2]
Microbiolo... [2]
Pharmacolo... [2]
Chemistry [1]
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Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis
期刊论文
OAI收割
CELL RESEARCH, 2016, 卷号: 26, 期号: 12, 页码: 1330-1344
作者:
Zhang, Lin
;
Xiao, Jianfeng
;
Xu, Jianrong
;
Fu, Tianran
;
Cao, Zhiwei
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
fatty acid biosynthesis
dehydratase
ACP
complex structure
Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization
期刊论文
OAI收割
BMC MICROBIOLOGY, 2009, 卷号: 9
作者:
Chen, Jing
;
Zhang, Liang
;
Zhang, Yu
;
Zhang, Haitao
;
Du, Jiamu
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Discovering Potent Inhibitors Against the beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) of Helicobacter pylori: Structure-Based Design, Synthesis, Bioassay, and Crystal Structure Determination
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2009, 卷号: 52, 期号: 8, 页码: 2465-2481
作者:
He, Lingyan
;
Zhang, Liang
;
Liu, Xiaofeng
;
Li, Xianghua
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization
期刊论文
OAI收割
BMC MICROBIOLOGY, 2009, 卷号: 9, 期号: 1, 页码: 91-91
作者:
Chen, J
;
Zhang, L
;
Zhang, Y
;
Zhang, HT
;
Du, JM
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2015/07/22
Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: Crystal structure characterization with enzymatic inhibition assay
期刊论文
OAI收割
PROTEIN SCIENCE, 2008, 卷号: 17, 期号: 11, 页码: 1971-1978
作者:
Zhang, Liang
;
Kong, Yunhua
;
Wu, Dalei
;
Zhang, Haitao
;
Wu, Jian
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
HpFabZ
quercetin
apigenin
(S)-sakuranetin
complex structure
inhibitory mechanism
Natural product juglone targets three key enzymes from Helicobacter pylori: inhibition assay with crystal structure characterization
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2008, 卷号: 29, 期号: 7, 页码: 870-876
作者:
Kong, Yun-hua
;
Zhang, Liang
;
Yang, Zheng-yi
;
Han, Cong
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
cystathionine gamma-synthase
malonyl-CoA : acyl carrier protein transacylase
beta-hydroxyacyl-ACP dehydratase
inhibitor type
complex structure