中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [26]
上海生物化学与细胞... [24]
天津工业生物技术研... [14]
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期刊论文 [170]
学位论文 [8]
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2021 [8]
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Biochemis... [18]
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Synthesis, and biological evaluation of EGFR/HER2-NAMPT conjugates for tumor treatment
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2023, 页码: 20
作者:
Ding, Mengyuan
;
Shen, Qianqian
;
Lu, Wei
;
Zhu, Shulei
  |  
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2023/10/17
EGFR
HER2
NAMPT
Resistance
Selectivity
Molecular docking
Systematic Analysis of Lysine Acetylation Reveals Diverse Functions in Azorhizobium caulinodans Strain ORS571
期刊论文
OAI收割
MICROBIOLOGY SPECTRUM, 2022, 页码: 18
作者:
Liu, Yanan
;
Liu, Xiaolin
;
Dong, Xiaoyan
;
Yin, Zhiqiu
;
Xie, Zhihong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/01/11
lysine acetylation
acetylome
Azorhizobium caulinodans ORS571
deacetylase
chemotaxis
D3AI-Spike: A deep learning platform for predicting binding affinity between SARS-CoV-2 spike receptor binding domain with multiple amino acid mutations and human angiotensin-converting enzyme 2
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2022, 卷号: 151, 页码: 8
作者:
Han, Jiaxin
;
Liu, Tingting
;
Zhang, Xinben
;
Yang, Yanqing
;
Shi, Yulong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
D3AI-Spike
ELISA
Protein -protein interaction
COVID-19
Deep learning
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2
期刊论文
OAI收割
LEUKEMIA, 2022
作者:
Yang, Jing
;
Weisberg, Ellen L.
;
Qi, Shuang
;
Ni, Wei
;
Mei, Husheng
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2022/02/14
NADP+ supply adjusts the synthesis of photosystem I in Arabidopsis chloroplasts
期刊论文
OAI收割
PLANT PHYSIOLOGY, 2022, 卷号: 189, 期号: 4, 页码: 2128-2143
作者:
Ji, Daili
;
Li, Qiuxin
;
Guo, Yinjie
;
An, Wenjing
;
Manavski, Nikolay
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/07
A mutation in Arabidopsis SAL1 alters its in vitro activity against IP3 and delays developmental leaf senescence in association with lower ROS levels
期刊论文
OAI收割
PLANT MOLECULAR BIOLOGY, 2022, 卷号: 108, 期号: 6, 页码: 549-563
作者:
Shirzadian-Khorramabad, Reza
;
Moazzenzadeh, Taghi
;
Sajedi, Reza H.
;
Jing, Hai-Chun
;
Hille, Jacques
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/03/07
Leaf senescence
Ageing
Age-related changes
Reactive oxygen species
SAL1
Arabidopsis
Enhanced activity and stability of Rhizomucor miehei lipase by mutating N-linked glycosylation site and its application in biodiesel production
期刊论文
OAI收割
FUEL, 2021, 卷号: 304, 页码: 11
作者:
Tian, Miao
;
Fu, Junying
;
Wang, Zhiyuan
;
Miao, Changlin
;
Lv, Pengmei
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/10/27
Rhizomucor miehei lipase
N-linked glycosylation site
Thermostability
Methanol tolerance
Biodiesel
Enhanced activity of Rhizomucor miehei lipase by directed saturation mutation of the propeptide
期刊论文
OAI收割
ENZYME AND MICROBIAL TECHNOLOGY, 2021, 卷号: 150, 页码: 8
作者:
Tian, Miao
;
Huang, Shaowei
;
Wang, Zhiyuan
;
Fu, Junying
;
Lv, Pengmei
  |  
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2021/11/01
Propeptide
RML
Enzyme activity
Directed saturation mutation
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
OAI收割
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2021/08/17
D3DistalMutation: a Database to Explore the Effect of Distal Mutations on Enzyme Activity
期刊论文
OAI收割
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2021, 卷号: 61, 期号: 5, 页码: 2499-2508
作者:
Wang, Xiaoyu
;
Zhang, Xinben
;
Peng, Cheng
;
Shi, Yulong
;
Li, Huiyu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/08/17