中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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广州生物医药与健康... [36]
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Structure-Based Drug Design of 2-Amino-[1,1′-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of
CCNE1
-Amplified Breast Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Wang, Chaofan
;
Fang, Yan
;
Zhou, Ziqin
;
Liu, Zhuoheng
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/09/26
Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:132/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-GenerationEpidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 9, 页码: 6840-6858
作者:
Chen, Hao
;
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Yuqing
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/03/21
Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-GenerationEpidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations br
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 9, 页码: 6840-6858
作者:
Chen, Hao
;
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Yuqing
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/08/16
The p300 Inhibitor A-485 Exerts Antitumor Activity in Growth Hormone Pituitary Adenoma
期刊论文
OAI收割
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2022, 页码: 10
作者:
Ji, Chenxing
;
Xu, Wen
;
Ding, Hong
;
Chen, Zhengyuan
;
Shi, Chengzhang
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/06/15
p300
A-485
growth hormone pituitary adenoma
Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFR(T790M/C797S) Mutants
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 7
作者:
Li, Shan
;
Zhang, Tao
;
Zhu, Su-Jie
;
Lei, Chong
;
Lai, Mengzhen
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/06/15
Epidermal Growth Factor Receptor (EGFR)
Resistant Mutation
C797S
Antitumor
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
OAI收割
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:114/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Electron-ion collider in China
期刊论文
OAI收割
FRONTIERS OF PHYSICS, 2021, 卷号: 16, 期号: 6, 页码: 78
作者:
Anderle, Daniele P.
;
Bertone, Valerio
;
Cao, Xu
;
Chang, Lei
;
Chang, Ningbo
  |  
收藏
  |  
浏览/下载:132/0
  |  
提交时间:2021/12/08
electron ion collider
nucleon structure
nucleon mass
exotic hadronic states
quantum chromodynamics
3D-tomography
helicity
transverse momentum dependent parton distribution
generalized parton distribution
energy recovery linac
polarization
spin rotator
Effect of FeCo2S4 on electrocatalytic I-3(-) reduction: Theoretical and experimental aspects
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2021, 卷号: 424
作者:
Zhang, Xiaoyun
;
Chen, Pin
;
Yang, Fan
;
Wang, Lian
;
Yin, Jie
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/01/10
FeCo2S4
Catalysis
Stability
Energy conversion
Density functional theory
Maize is stressed by salt rather than water under drip irrigation with soil matric potential higher than-50 kPa in an arid saline area
期刊论文
OAI收割
JOURNAL OF AGRONOMY AND CROP SCIENCE, 2021, 页码: 15
作者:
Zhang, Tibin
;
Ji, Xiangxiang
;
Zhan, Xiaoyun
;
Ding, Yuntao
;
Zou, Yufeng
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/06/10
crop salt production function
crop salt tolerance
mulched drip irrigation
readily available water
soil matric potential
water‐
use efficiency