机构

• 合肥物质科学研究院 [8]
• 高能物理研究所 [1]
• 武汉岩土力学研究所 [1]
• 沈阳自动化研究所 [1]

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [11]

发表日期

• 2021 [1]
• 2020 [1]
• 2019 [1]
• 2018 [4]
• 2017 [2]
• 2012 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 A two-stage temporal proposal network for precise action localization in untrimmed video 期刊论文  OAI收割 International Journal of Machine Learning and Cybernetics, 2021, 卷号: 12, 期号: 8, 页码: 2199-2211 作者:  Wang F(王斐);  Wang, Guorui;  Du, Yuxuan;  He, Zhenquan;  Jiang Y(姜勇)   |  收藏  |  浏览/下载：28/0  |  提交时间：2021/04/24 Action detection  Correctness discriminator  Extended context pooling  Temporal context regression   Discovery of 6 '-chloro-N-methyl-5 '-(phenylsulfonamido)-[3,3 '-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 188 作者:  Liang, Xiaofei;  Jiang, Zongru;  Huang, Zhenghui;  Li, Feng;  Chen, Cheng   |  收藏  |  浏览/下载：41/0  |  提交时间：2020/11/26 PI4K kinase  Kinase inhibitor  Malaria  Blood stage  Liver stage   Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models 期刊论文  OAI收割 CANCER LETTERS, 2019, 页码: 105-114 作者:  Lu, Tingting;  Chen, Cheng;  Wang, Aoli;  Jiang, Zongru;  Qi, Ziping   |  收藏  |  浏览/下载：41/0  |  提交时间：2020/07/14 cKIT T670I mutant  Activation loop mutants  Drug resistance   Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81 作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen   |  收藏  |  浏览/下载：52/0  |  提交时间：2019/01/11 ABL kinase  Kinase inhibitor  ABL mutant  CML   Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916 作者:  Wang, Beilei;  Wu, Jiaxin;  Wu, Yun;  Chen, Cheng;  Zou, Fengming   |  收藏  |  浏览/下载：77/0  |  提交时间：2019/12/25 CDK9  Kinase inhibitor  Structure-activity relationship  Leukemia   Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846 作者:  Liang, Xiaofei;  Li, Feng;  Chen, Cheng;  Jiang, Zongru;  Wang, Aoli   |  收藏  |  浏览/下载：41/0  |  提交时间：2019/12/10 PI3K delta  Kinase inhibitor  Acute myeloid leukemia  Structure-activity relationship   Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFR alpha kinase inhibitor for PDGFR alpha driving chronic eosinophilic leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 期号: 无, 页码: 366-384 作者:  Wang, Qiang;  Liu, Feiyang;  Qi, Shuang;  Qi, Ziping;  Yan, Xiao-E.   |  收藏  |  浏览/下载：76/0  |  提交时间：2019/06/10 PDGFR kinase  Type II inhibitor  Kinase inhibitor  CEL   Discovery of N-(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 期号: 无, 页码: 674-697 作者:  Chen, Yongfei;  Wu, Jiaxin;  Wang, Aoli;  Qi, Ziping;  Jiang, Taoshan   |  收藏  |  浏览/下载：892/0  |  提交时间：2018/08/17 Egfr  Alk  Dual Kinase Inhibitor  Non-small Cell Lung Cancer   Discovery of 2-((3-Acrylamido-4-methylphenyl)amino)-N-(2-methyl5-(3,4,5-trimethoxybenzamido)phenyI)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-BMX-078) as a Highly Potent and Selective Type II Irreversible Bone Marrow Kinase in the X Chromosome (BMX) Kinase Inhibitor 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 5, 页码: 1793-1816 作者:  Liang, Xiaofei;  Lv, Fengchao;  Wang, Beilei;  Yu, Kailin;  Wu, Hong   |  收藏  |  浏览/下载：905/0  |  提交时间：2018/07/04 岩石膨胀界限抗渗强度及在底板突水评价中应用 期刊论文  OAI收割 采矿与安全工程学报, 2012, 期号: 01, 页码: 95-100 作者:  段宏飞;  姜振泉;  王一栋;  邵明喜;  赵丽娟   |  收藏  |  浏览/下载：23/0  |  提交时间：2018/06/25 岩石膨胀界限抗渗强度  底板突水  Rqd  全应力应变伺服试验  渗透率