中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [40]
上海硅酸盐研究所 [4]
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期刊论文 [49]
会议论文 [4]
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Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapy
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 22
作者:
Bai, Wenjing
;
Xu, Jinxin
;
Gu, Wenbin
;
Wang, Danyang
;
Cui, Ying
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
Discovery of KW0113 as a First and Effective PROTAC Degrader of DNMT1 Protein
期刊论文
OAI收割
CHEMMEDCHEM, 2024, 页码: 16
作者:
Wang, Huihui
;
Wang, Zhaoliang
;
Hu, Linghao
;
Yang, Bingjie
;
Zong, Liangyi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/12/16
Degrader
DNMT1
DNA methylation
PROTAC
Development of a First-in-Class DNMT1/HDAC Inhibitor with Improved Therapeutic Potential and Potentiated Antitumor Immunity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 18, 页码: 16480-16504
作者:
Chang, Yingjie
;
Guo, Huahui
;
Li, Xue
;
Zong, Liangyi
;
Wei, Jiale
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/10/21
Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2024, 页码: 12
作者:
Zhang, Huimin
;
Xu, Dounan
;
Huang, Hongchan
;
Jiang, Hao
;
Hu, Linghao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/07
PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 3, 页码: 419-433
作者:
Tao, Hongru
;
Jin, Chen
;
Zhou, Liyuan
;
Deng, Zhenzhong
;
Li, Xiao
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/04/09
Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555
作者:
Li, Ennian
;
Wang, Kai
;
Zhang, Bei
;
Guo, Siqi
;
Xiao, Senhao
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2022/08/16
DNMT1 inhibitor
A549 cell lines
HCT116 cell lines
antitumor activity
pharmacokinetic
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:
Du, Daohai
;
Xu, Dandan
;
Zhu, Licheng
;
Stazi, Giulia
;
Zwergel, Clemens
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2021/08/17
Regional Differences in the Prevalence of Anaemia and Associated Risk Factors among Infants Aged 0-23 Months in China: China Nutrition and Health Surveillance
期刊论文
OAI收割
NUTRIENTS, 2021, 卷号: 13, 期号: 4, 页码: 12
作者:
Li, Shujuan
;
Bo, Yacong
;
Ren, Hongyan
;
Zhou, Chen
;
Lao, Xiangqian
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/07/09
anaemia
0–
23-month-old infants
regional differences
risk factors
China
Regional Differences in the Prevalence of Anaemia and Associated Risk Factors among Infants Aged 0-23 Months in China: China Nutrition and Health Surveillance
期刊论文
OAI收割
NUTRIENTS, 2021, 卷号: 13, 期号: 4, 页码: 12
作者:
Li, Shujuan
;
Bo, Yacong
;
Ren, Hongyan
;
Zhou, Chen
;
Lao, Xiangqian
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/07/09
anaemia
0–
23-month-old infants
regional differences
risk factors
China
Retention of nitrogen and phosphorus in Lake Chaohu, China: implications for eutrophication management
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2020, 卷号: 27, 期号: 33, 页码: 41488-41502
作者:
Wang, Yanping
;
Kong, Xiangzhen
;
Peng, Zhaoliang
;
Zhang, Hui
;
Liu, Gang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/11/15