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浏览/检索结果: 共4782条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11 作者:  Guma, Samuel Desta;  Song, Kang;  Sun, Haiguo;  Yang, Lei;  Zhou, Zhaoyin   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 SARS-CoV-2  3CL(pro) inhibitors  Thioamide derivatives  Spiropyrrolidine derivatives  Nirmatrelvir  HCoV-OC43  Antiviral  Metabolic stability   First polarization study of the M87 jet and active galactic nuclei at submillimeter wavelengths with ALMA 期刊论文  OAI收割 ASTRONOMY & ASTROPHYSICS, 2025, 卷号: 699 作者:  Goddi, Ciriaco;  Carlos, Douglas F.;  Crew, Geoffrey B.;  Matthews, Lynn D.;  Messias, Hugo   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/08/25 black hole physics  magnetic fields  polarization  radiation mechanisms: non-thermal  instrumentation: interferometers  instrumentation: polarimeters   Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins 期刊论文  OAI收割 SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7 作者:  Cao, Zhen;  Aharonian, F.;  Axikegu;  Bai, Y. X.;  Bao, Y. W.   |  收藏  |  浏览/下载：33/0  |  提交时间：2025/06/10 gamma rays  cosmic rays  supernova remnant  young massive cluster  pulsar   Noise Reduction Method for Radio Astronomy Single Station Observation Based on Wavelet Transform and Mathematical Morphology 期刊论文  OAI收割 RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7 作者:  Qin, Ming-Wei;  Tang, Rui;  Zhou, Ying-Hui;  Lan, Chang-Jun;  Fu, Wen-Hao   |  收藏  |  浏览/下载：20/0  |  提交时间：2025/07/03 methods: data analysis  techniques: image processing  techniques: spectroscopic  Sun: radio radiation  methods: numerical   Identification of Cannabigerol-Derived Dual CB2 Receptor Agonists and TRPM8 Antagonists with Anti-Inflammatory and Analgesic Activities 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 13, 页码: 13335-13357 作者:  Yang, Wenjiao;  Sun, Haiguo;  Ji, Jing;  Chen, Hai;  Cheng, Jiaxin   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Small-Molecule Probe [68Ga]Ga-SMIC-2501 Targeting the V-Domain Immunoglobulin Suppressor of T Cell Activation Protein for Positron Emission Tomography Imaging 期刊论文  OAI收割 MOLECULAR PHARMACEUTICS, 2025, 页码: 11 作者:  Wang, Gang;  Cao, Rui;  Liu, Shumei;  Qian, Kun;  Sun, Luming   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/08/20 VISTA  immunecheckpoint  immunotherapy  PET  tumor microenvironment  molecular imaging   Detection of an Orphan X-Ray Flare from a Blazar Candidate EP240709a with the Einstein Probe 期刊论文  OAI收割 ASTROPHYSICAL JOURNAL, 2025, 卷号: 984, 期号: 1 作者:  Liu, Mingjun;  Zhang, Yijia;  Wang, Yun;  Xue, Rui;  Buckley, David   |  收藏  |  浏览/下载：27/0  |  提交时间：2025/05/05 Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14 作者:  Wu, Xinyuan;  Li, Shunyao;  Liang, Ting;  Yu, Qing;  Zhang, Yiwei   |  收藏  |  浏览/下载：22/0  |  提交时间：2025/06/23 Activity-based protein profiling data  Covalent DNA-encoded chemical library  Covalent ligand selection  Lysine-targeting covalent inhibitors   Substrate recognition and cleavage mechanism of the monkeypox virus core protease 期刊论文  OAI收割 NATURE, 2025, 页码: 29 作者:  Gao, Yan;  Xie, Xiong;  Zhang, Xiaoyu;  Cao, Junyuan;  Lan, Weiqi   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/08/20 Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796 作者:  Hu, Liuyan;  Zhao, Zhi;  Zhang, Shujing;  Yang, Lei   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/06/23 COVID-19  SARS-CoV-2  3CL protease  Peptidomimetic inhibitors  Tetrahydropyrrole spirodihydroindolone