中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海硅酸盐研究所 [64]
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期刊论文 [327]
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Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:
Zeng, Yanping
;
Xiao, Jian
;
Shi, Li
;
Li, Yangsha
;
Xu, Yuanxin
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2025/04/01
LC3B
CDK9
Degradation
Protein complex
Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Constraints on the continental weathering intensity through the Permian using lithium isotopes of well-preserved brachiopod shells
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2024, 卷号: 648, 页码: 15
作者:
Wang, Wen-qian
;
Zhang, Feifei
;
Liu, Chun-Yao
;
von Strandmann, Philip A. E. Pogge
;
Xiong, Guolin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/03/28
Brachiopod shells
Lithium isotopes
Continental weathering
Permian
Carbonate diagenesis
Petrology of Tourmaline-Bearing Blueschist from SW Tianshan, China, and Its Implication in B-Rich Fluid Migration in Subduction Zone
期刊论文
OAI收割
JOURNAL OF PETROLOGY, 2024, 卷号: 65, 期号: 11, 页码: 23
作者:
Shen, Tingting
;
Hu, Han
;
Zhang, Lifei
;
Xu, Jie Dudo
;
Tian, Zuolin
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/01
Boron isotopes
tourmaline
serpentinites
subduction zone fluid
China
Design, Synthesis, and Biological Evaluation of HDAC Inhibitors Containing Natural Product-Inspired
N
-Linked 2-Acetylpyrrole Cap
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 19, 页码: 26
作者:
Zhang, Han
;
Shen, Qianqian
;
Hu, Zhu
;
Wu, Pei-Qian
;
Chen, Yi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/11/26
HDAC inhibitors
anti-cancer activity
natural products
pyrrole derivatives
molecular docking
molecular dynamics simulation
Structural Optimization of Isoquinoline Derivatives from Lycobetaine and Their Inhibitory Activity against Neuroendocrine Prostate Cancer Cells
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 18, 页码: 28
作者:
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/11/05
NEPC
natural product
natural product derivatives
lycobetaine
FMP-6-S4 impeded Aβ
42
induced SH-SY5Y cell injury by targeting cyclophilin D
期刊论文
OAI收割
JOURNAL OF FUNCTIONAL FOODS, 2024, 卷号: 119, 页码: 9
作者:
Gao, Pengcheng
;
Li, Saijuan
;
Wang, Yuyong
;
Wu, Fangge
;
Jin, Can
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/05
Alzheimer's disease
Fructus Mori
Amyloid beta
Cyclophilin D
Mitochondrial permeability transition pore
Glycopeptide
Fine-tuning large language models for chemical text mining
期刊论文
OAI收割
CHEMICAL SCIENCE, 2024, 页码: 12
作者:
Zhang, Wei
;
Wang, Qinggong
;
Kong, Xiangtai
;
Xiong, Jiacheng
;
Ni, Shengkun
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/07/12
A Pennsylvanian rugose coral assemblage from eastern Junggar Basin, Northwest China
期刊论文
OAI收割
PALAEOWORLD, 2024, 卷号: 33, 期号: 3, 页码: 650-663
作者:
Yang, Sun-Rong
;
Yao, Le
;
Hou, Zhang-Shuai
;
Ye, Xun-Yan
;
Li, Ying
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/08/28
rugose coral
Palaeotethys Ocean
Moscovian-Kasimovian stage
Junggar Basin
Northwest China
KinomeMETA: a web platform for kinome-wide polypharmacology profiling with meta-learning
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2024, 页码: 9
作者:
Li, Zhaojun
;
Qu, Ning
;
Zhou, Jingyi
;
Sun, Jingjing
;
Ren, Qun
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/06/27