中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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期刊论文 [388]
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Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:
Zeng, Yanping
;
Xiao, Jian
;
Shi, Li
;
Li, Yangsha
;
Xu, Yuanxin
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/04/01
LC3B
CDK9
Degradation
Protein complex
Strain-rate and temperature dependent optimum precipitation sizes for strengthening in medium-entropy alloys
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PLASTICITY, 2025, 卷号: 187, 页码: 19
作者:
Yuan, Ziyi
;
Chen, Cen
;
Zhang, Xu
;
Zhou, Lingling
;
Wu, Xiaolei
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/07
High/medium-entropy alloys
Nanoprecipitates
Strain rate effects
Temperature effects
Precipitation strengthening
Geometrically necessary dislocations
A systematic review of the progress of research on comprehensive benefit assessment of national-level ecological protection projects in China
期刊论文
OAI收割
ENVIRONMENTAL IMPACT ASSESSMENT REVIEW, 2025, 卷号: 112, 页码: 107816
作者:
He, Meixin
;
Xu, Jie
;
Xiao, Yu
;
Gu, Xintian
;
Pang, Qi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/03/18
Comprehensive benefits assessment
National Ecological Protection Project (EPPs)
Intrinsic mechanisms
Sustainable development goals
A novel cocrystal of indole-3-propionic acid and nicotinamide: Structure design, preparation, characterization and preliminary physiochemical properties evaluation
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1322, 页码: 9
作者:
Guo, Jiacheng
;
Xu, Lingling
;
You, Wen
;
Ji, Yuze
;
Chen, Dongying
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/12/25
Indole-3-propionic acid
Nicotinamide
Cocrystal
Solubility
Permeability
Stability
Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 19
作者:
Yin, Wen
;
Xu, Heng
;
Bai, Zhonghao
;
Wu, Yue
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
B(MIDA)-directed site-selective intermolecular halofluoroalkylation of alkenes: synthesis of diversely functionalized building blocks
期刊论文
OAI收割
CHEMICAL SCIENCE, 2025, 页码: 8
作者:
Wu, Hengbo
;
Luo, Ruitong
;
Peng, Jingjing
;
Han, Zijian
;
Zhang, Renjie
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
;
Song, Kang
;
Yang, Feipu
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives
The structure elucidation and alleviating effect on liver fibrosis in vivo of pectin-like polysaccharide isolated from
Buddleja
officinalis
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 284, 页码: 14
作者:
Zong, Jianing
;
Li, Yun
;
Zhou, Wanqi
;
Mao, Mengfei
;
Xu, Xin
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/01/14
Buddleja officinalis
Polysaccharides
Pectin
Liver fibrosis
Harnessing acylhydrazone-oxime exchange reaction to achieve diverse synthesis of glycosite-specific antibody-drug conjugates
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 页码: 9
作者:
Xia, Fei
;
Liu, Zhi
;
Hang, Jiaying
;
Xu, Hao
;
Xiao, Yuting
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01