机构

• 上海药物研究所 [35]
• 心理研究所 [3]
• 化学研究所 [2]
• 成都生物研究所 [1]
• 国家天文台 [1]
• 高能物理研究所 [1]
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采集方式

• OAI收割 [43]
• iSwitch采集 [2]

内容类型

• 期刊论文 [44]
• 学位论文 [1]

发表日期

• 2025 [1]
• 2024 [2]
• 2023 [2]
• 2022 [4]
• 2021 [2]
• 2020 [2]
• 更多

学科主题

• Energy & F... [1]
• Engineerin... [1]
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• 创伤心理学 [1]
• 医学心理学 [1]

筛选

浏览/检索结果: 共45条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10 作者:  Zeng, Yanping;  Xiao, Jian;  Shi, Li;  Li, Yangsha;  Xu, Yuanxin   |  收藏  |  浏览/下载：41/0  |  提交时间：2025/04/01 LC3B  CDK9  Degradation  Protein complex   Single Amine or Guanidine Modification on Norvancomycin and Vancomycin to Overcome Multidrug-Resistance through Augmented Lipid II Binding and Increased Membrane Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 22, 页码: 20639-20663 作者:  Bian, Xiaolei;  Chen, Zhifu;  Li, Fang;  Xie, Yuanyuan;  Li, Yi   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/12/11 A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression 期刊论文  OAI收割 ANTIVIRAL RESEARCH, 2024, 卷号: 221, 页码: 14 作者:  Yang, Li;  Gong, Ying;  Liu, Feifei;  Chen, Wuhong;  Wang, Xinran   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/02/19 Hepatitis B virus  Capsid assembly  Phthalazinone derivatives  Apoptosis   A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8 作者:  Chen, Wuhong;  Gong, Ying;  Long, Guozhang;  Wang, Xinran;  Yang, Yurong   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 HBV  Capsid assembly modulators  Prodrug  Hepatitis B surface antigen   Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037 作者:  Li, Daqiang;  Zhang, Zhuo;  Li, Yalei;  Wang, Xinyi;  Zhong, Hanyue   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/10/17 Discovery of potent ebola entry inhibitors with (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 12 作者:  Han, Sheng;  Li, Heng;  Chen, Weixiong;  Yang, Li;  Tong, Xiankun   |  收藏  |  浏览/下载：31/0  |  提交时间：2022/11/11 Ebola virus  Entry inhibitor  Structural optimization   Experimental study on hydraulic fracturing behavior of frozen clayey silt and hydrate-bearing clayey silt 期刊论文  OAI收割 FUEL, 2022, 卷号: 322, 期号: -, 页码: - 作者:  Ma, Xiaolong;  Jiang, Dandan;  Sun, Youhong;  Li, Shengli   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/08/02 Clayey silt  Gas hydrate  Hydraulic fracturing  Fracture propagation  Fracture initiation  Fracture morphology   Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 14 作者:  Chen, Jingjing;  He, Huixin;  Wei, Aihuan;  Li, Yalei;  Cheng, Gang   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/08/16 PROTAC  Pyrrolopyridone  BRD4 S  Selectivity   Discovery of highly potent SARS-CoV-2 M-pro inhibitors based on benzoisothiazolone scaffold 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 58, 页码: 6 作者:  Chen, Weixiong;  Feng, Bo;  Han, Sheng;  Wang, Peipei;  Chen, Wuhong   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/06/15 COVID-19  SARS-CoV-2  Main protease inhibitors  Benzoisothiazolone   Discovery of Potent Antiallergic Agents Based on an o-Aminopyridinyl Alkynyl Scaffold 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 18, 页码: 13588-13603 作者:  Xie, Zhicheng;  Xiang, Caigui;  Li, Xin;  Fan, Chen;  Chen, Taiwen   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/21