中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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金属研究所 [32]
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期刊论文 [301]
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
The Overview and Trial Observations of AIMS
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7
作者:
Deng, Yuanyong
;
Wang, Dongguang
;
Hua, Jianwen
;
Xu, Songbo
;
Liang, Ming
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2025/07/14
Sun: infrared
methods: observational
instrumentation: spectrographs
Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679
作者:
Jin, Yuheng
;
Qi, Xuxin
;
Yu, Xiaoli
;
Cheng, Xirui
;
Chen, Boya
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2025/06/23
HDAC7
PROTAC
Selectivity
Hematologic malignancies
Non-enzymatic function
Dietary Differentiation Mitigates Interspecific Interference Competition Between Sympatric Pallas's Cats (Otocolobus manul) and Red Foxes (Vulpes vulpes)
期刊论文
OAI收割
ANIMALS, 2025, 卷号: 15, 期号: 9
作者:
Wang, Dong
;
Li, Quanbang
;
Gao, Jingyu
;
Hou, Luyi
;
Zou, Yanjun
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/11/27
coexistence
trophic niche
dietary composition
Pallas's cat (Otocolobus manul)
red fox (Vulpes vulpes)
Sanjiangyuan National Park
Increased Temporal Overlap in Diel Activity Patterns Potentially Intensifies Interspecific Competition Among Sympatric Large Carnivores in the Sanjiangyuan Region of China
期刊论文
OAI收割
ANIMALS, 2025, 卷号: 15, 期号: 14
作者:
Wang, Dong
;
Li, Quanbang
;
Gao, Jingyu
;
Su, Xu
;
Lian, Xinming
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/11/27
carnivores
infrared camera trap
activity time overlap
interspecific interference
sympatric coexistence
Financial fraud detection for Chinese listed firms: Does managers' abnormal tone matter?
期刊论文
OAI收割
EMERGING MARKETS REVIEW, 2024, 卷号: 62, 页码: 14
作者:
Li, Jingyu
;
Guo, Ce
;
Lv, Sijia
;
Xie, Qiwei
;
Zheng, Xiaolong
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2024/09/09
Financial fraud
Managers' abnormal tone
Machine learning
Feature selection
Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 28
作者:
Duan, Haiting
;
Zhang, Jingyu
;
Gui, Renzhao
;
Lu, Yang
;
Pang, Ao
  |  
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2024/08/20
Microstructural evolution and formation of fine grains during fatigue crack initiation process of laser powder bed fusion Ni-based superalloy
期刊论文
OAI收割
ADDITIVE MANUFACTURING, 2024, 卷号: 85, 页码: 17
作者:
Shi, Tao
;
Li, Jianghua
;
Gao, Guhui
;
Sun, Jingyu
;
Yang, Zhigang
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2024/06/27
Microstructure
Competitive fatigue failure mechanism
Laser powder bed fusion (LPBF)
Grain refinement
Precipitate dissolution
Need for uniqueness and adolescents' problematic internet use: longitudinal evidence on the role of stress and ego depletion
期刊论文
OAI收割
CURRENT PSYCHOLOGY, 2024, 页码: 10
作者:
Ding, Huimin
;
Geng, Jingyu
;
Huang, Feng
;
Lei, Li
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2024/05/05
Need for uniqueness
Problematic internet use
Stress
Ego depletion
Adolescents
Activating CD8
+
T Cells by Pt(IV) Prodrug-Based Nanomedicine and aPD-L1 Antibody for Enhanced Cancer Immunotherapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 15
作者:
Wang, Bin
;
Zhou, Jingyu
;
Li, Ruitong
;
Tang, Dongsheng
;
Cao, Zheng
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2024/04/09
chemotherapy
immunotherapy
immunogenic cell death
tumor immune microenvironment