中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Advancing active compound discovery for novel drug targets: insights from AI-driven approaches
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12
作者:
Wang, Xing-you
;
Chen, Yang
;
Li, Yu-fan
;
Wei, Chao-yang
;
Liu, Meng-ya
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/08/20
AI-driven drug discovery
novel drug targets
molecular design
ligand exploration
phenotypic drug discovery
undruggable targets
A post-common-envelope binary with double-peaked Balmer emission lines from TMTS
期刊论文
OAI收割
Astronomy and Astrophysics, 2025, 卷号: 698
作者:
Liu, Qichun
;
Wang, Xiaofeng
;
Lin, Jie
;
Wu CY(吴程远)
;
Li, Chunqian
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2025/06/10
techniques: radial velocities
binaries: spectroscopic
stars: evolution
white dwarfs
stars: winds
outflows
Enteric neuronal Piezo1 maintains mechanical and immunological homeostasis by sensing force
期刊论文
OAI收割
CELL, 2025, 卷号: 188, 期号: 9, 页码: 36
作者:
Xie, Zili
;
Rose, Lillian
;
Feng, Jing
;
Zhao, Yonghui
;
Lu, Yisi
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/07/25
Proteogenomic characterization of non-functional clinically relevant subgroups
期刊论文
OAI收割
CANCER CELL, 2025, 卷号: 43, 期号: 4, 页码: 36
作者:
Ji, Shunrong
;
Cao, Lihua
;
Gao, Jing
;
Du, Yang
;
Ye, Zeng
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2025/06/23
Mantle metasomatism by subducted Indian continental crust: Evidence from post-collisional basaltic ultrapotassic rocks in southern Tibetan plateau
期刊论文
OAI收割
LITHOS, 2025, 卷号: 498, 页码: 11
作者:
Zhang, Miao-Yan
;
Hao, Lu-Lu
;
Qi, Yue
;
Wang, Qiang
;
Kerr, Andrew C.
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2025/04/03
Mo - B isotopes
Post-collisional ultrapotassic rocks
Continental crust recycling
Crust-mantle interaction
Tibetan Plateau
Nonlinear microbial thermal response and its implications for abrupt soil organic carbon responses to warming
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 2763
作者:
Yu, Kailiang
;
He, Lei
;
Niu, Shuli
;
Wang, Jinsong
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2025/04/21
Terrestrial ecosystem response to Early Cretaceous global environmental change: A calibrated, high-resolution Aptian record from Northeast China
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2025, 卷号: 653, 页码: 13
作者:
Sun, Ming-Dao
;
Lin, Qin
;
Ramezani, Jahandar
;
Liu, Jiang-Si
  |  
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2025/04/03
Early Cretaceous
Aptian
CA-ID-TIMS geochronology
Astrochronology
Carbon isotope stratigraphy
Integration of deep neural network modeling and LC-MS-based pseudo-targeted metabolomics to discriminate easily confused ginseng species
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2025, 卷号: 15, 期号: 1, 页码: 12
作者:
Jiang, Meiting
;
Sha, Yuyang
;
Zou, Yadan
;
Xu, Xiaoyan
;
Ding, Mengxiang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2025/04/01
Liquid chromatography-mass spectrometry
Pseudo-targeted metabolomics
Deep neural network
Species differentiation
Ginseng
Divergence of alpine plant populations of three Gentianaceae species in the Qinling sky Island
期刊论文
OAI收割
BMC PLANT BIOLOGY, 2025, 卷号: 25, 期号: 1
作者:
Fu, Peng-Cheng
;
Mo, Bing-Jie
;
Wan, He-Xin
;
Yang, Shu-Wen
;
Xing, Rui
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/11/27
Climatic change
Genetic divergence
Genomic SNPs
Gentianaceae
Plastome
Qinghai-tibet plateau
Qinling mountains