机构

• 上海药物研究所 [162]
• 昆明植物研究所 [6]

采集方式

• OAI收割 [168]

内容类型

• 期刊论文 [120]
• 会议论文 [34]
• 专利 [14]

发表日期

• 2023 [4]
• 2020 [3]
• 2019 [5]
• 2018 [10]
• 2017 [6]
• 2016 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共168条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers 期刊论文  OAI收割 MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925 作者:  Zhou, Wei;  Fang, Peng;  Yu, Dongan;  Ren, Hongyuan;  You, Meng   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/10/17 Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 11, 页码: 7179-7204 作者:  Dong, Qian;  Tong, Mengya;  Yu, Xiaolu;  Wang, Lei;  Ao, Jiwei   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/10/17 Modular Biomimetic Strategy Enabled Discovery of Simplified Pseudo-Natural Macrocyclic P-Glycoprotein Inhibitors Capable of Overcoming Multidrug Resistance 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 4, 页码: 2550-2565 作者:  Liu, Bo;  Yu, Xueni;  Liu, Liping;  Wang, Lei;  Wang, Jie   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/27 Combined inhibition of PARP and ATR synergistically potentiates the antitumor activity of HER2-targeting antibody-drug conjugate in HER2-positive cancers 期刊论文  OAI收割 AMERICAN JOURNAL OF CANCER RESEARCH, 2023, 卷号: 13, 期号: 1, 页码: 161-+ 作者:  Li, Yongpeng;  Li, Lin;  Fu, Haoyu;  Yao, Qing;  Wang, Lei   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/10/17 Antibody-drug conjugate  DS-8201  PARP  ATR  synergy  DNA damage   Trastuzumab in combination with PEGylated interferon-alpha 1b exerts synergistic antitumor activity through enhanced inhibition of HER2 downstream signaling and antibody-dependent cellular cytotoxicity 期刊论文  OAI收割 AMERICAN JOURNAL OF CANCER RESEARCH, 2022, 卷号: 12, 期号: 2, 页码: 549-561 作者:  Xu, Piaopiao;  Chen, Xiangling;  Xu, Yongping;  Fu, Li;  Li, Yun   |  收藏  |  浏览/下载：173/0  |  提交时间：2022/06/15 Trastuzumab  PEGylated IFN-alpha 1b  ADCC  HER2-positive cancer  synergistic effect   Preclinical characterization of LOXO-338, a novel, oral and selective BCL2 inhibitor. 期刊论文  OAI收割 CANCER RESEARCH, 2021, 卷号: 81, 期号: 13, 页码: 1 作者:  Brandhuber, Barbara;  Ku, Karin;  Lallena, Maria J.;  Baquero, Carmen;  Choy, Regina   |  收藏  |  浏览/下载：47/0  |  提交时间：2021/11/04 Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells 期刊论文  OAI收割 THORACIC CANCER, 2021, 页码: 9 作者:  Zhang, Mi;  Quan, Haitian;  Fu, Li;  Li, Yun;  Fu, Haoyu   |  收藏  |  浏览/下载：65/0  |  提交时间：2021/05/24 EGFR‐  mutant non‐  small cell lung cancer  famitinib  HS‐  10296  multi‐  targeted tyrosine kinase inhibitor  third‐  generation EGFR inhibitor   TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models 期刊论文  OAI收割 AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 卷号: 11, 期号: 4, 页码: 1632-1645 作者:  Wang, Lei;  Zhu, Xi;  Li, Lili;  Li, Lin;  Fu, Li   |  收藏  |  浏览/下载：26/0  |  提交时间：2021/06/11 PARP  DNA damage  hematologic toxicity  beta-glucuronidase  tumor selectivity   YES1amplification confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive cancer 期刊论文  OAI收割 BRITISH JOURNAL OF CANCER, 2020, 页码: 12 作者:  Wang, Lei;  Wang, Quanren;  Xu, Piaopiao;  Fu, Li;  Li, Yun   |  收藏  |  浏览/下载：20/0  |  提交时间：2020/12/24 Pd-Catalyzed Decarboxylative Olefination: Stereoselective Synthesis of Polysubstituted Butadienes and Macrocyclic P-glycoprotein Inhibitors 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 22, 页码: 9982-9992 作者:     |  收藏  |  浏览/下载：42/0  |  提交时间：2020/12/24