机构

• 上海药物研究所 [12]
• 物理研究所 [1]
• 高能物理研究所 [1]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [14]

发表日期

• 2023 [1]
• 2022 [3]
• 2021 [1]
• 2020 [1]
• 2019 [1]
• 2018 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共14条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764 作者:  Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/01/26 Small molecule inhibitor  Tumor microenvironment  Immune-checkpoint  immune-deficient mouse models  including temozolomide (TMZ) insensitive tumors. Notably   ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9 作者:  Song, Peiran;  Bai, Gang;  Chan, Shingpan;  Zhang, Tao;  Tong, Linjiang   |  收藏  |  浏览/下载：43/0  |  提交时间：2023/04/10 Bruton's tyrosine kinase  interleukin-2-inducible T cell kinase  ASK120067  B-cell lymphoma  T-cell leukemia   SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors 期刊论文  OAI收割 CELL RESEARCH, 2022, 页码: 21 作者:  Wang, Xiaomin;  Chen, Ziqi;  Xu, Jun;  Tang, Shuai;  An, Nan   |  收藏  |  浏览/下载：63/0  |  提交时间：2022/06/15 Discovery of Pteridine-7(8H)-one Derivatives as Potent and Selective Inhibitors of Bruton's Tyrosine Kinase (BTK) 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 3, 页码: 2694-2709 作者:  Dou, Dou;  Diao, Yanyan;  Sha, Wenjie;  Su, Rongrong;  Tong, Linjiang   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/08/16 Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文  OAI收割 Molecular Cancer, 2021, 卷号: 20, 期号: 1 作者:  Zhang,Tao;  Qu,Rong;  Chan,Shingpan;  Lai,Mengzhen;  Tong,Linjiang   |  收藏  |  浏览/下载：71/0  |  提交时间：2021/11/04 Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文  OAI收割 MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15 作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang   |  收藏  |  浏览/下载：94/0  |  提交时间：2020/07/01 Non-small cell lung cancer (NSCLC)  EGFR T790M  Small-molecule inhibitor  Drug resistance  Ack1   Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFR(L858R/T790M/C797S)) 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7302-7308 作者:  Shen, Jiayi;  Zhang, Tao;  Zhu, Su-Jie;  Sun, Min;  Tong, Linjiang   |  收藏  |  浏览/下载：44/0  |  提交时间：2020/07/01 Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 428-441 作者:  Zhang, Qiumeng;  Shen, Qianqian;  Gao, Lixin;  Tong, Linjiang;  Li, Jia   |  收藏  |  浏览/下载：52/0  |  提交时间：2019/01/08 Aurora A  Aurora B  KDR  Multi-targeted  Anticancer  Heterocyclic   identificationofcompoundd2923asanovelantitumoragenttargetingcsf1r 期刊论文  OAI收割 actapharmacologicasinica, 2018, 卷号: 039, 期号: 011, 页码: 1768 作者:  Liu Yingqiang;  Wang Yanan;  Lu Xiaoyun;  Tong Linjiang;  Li Yan   |  收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01 肿瘤组织  代理人  apoptosis  生长抑制率  复合  指向  鉴定  巨噬细胞   Aspirin Inhibits Cancer Metastasis and Angiogenesis via Targeting Heparanase 期刊论文  OAI收割 CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 期号: 20, 页码: 6267-6278 作者:  Dai, Xiaoyang;  Yan, Juan;  Fu, Xuhong;  Pan, Qiuming;  Sun, Danni   |  收藏  |  浏览/下载：40/0  |  提交时间：2019/01/08