中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共211条,第1-10条 帮助

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Novel Aryl Sulfonium Modification on Vancomycin to Tackle MRSA and VRE In Vitro and In Vivo through Dual Enhanced Cell-Wall and Membrane Inhibition 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 8, 页码: 8310-8329
作者:  
Xie, Yuanyuan;  Wang, Xiaowen;  Chang, Taopeng;  Chen, Zhifu;  Luo, Youhong
  |  收藏  |  浏览/下载:2/0  |  提交时间:2025/06/23
A Rationally Designed Sulfonium Lipoglycopeptide with Micelles Self-Assembly to Combat Multidrug Resistance via Dual Enhanced Cell Wall-Membrane Inhibition and T7SS Proteins Downregulation 期刊论文  OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 15, 页码: 12587-12603
作者:  
Xie, Yuanyuan;  Wang, Xiaowen;  Li, Fang;  Chen, Zhifu;  Li, Qun
  |  收藏  |  浏览/下载:1/0  |  提交时间:2025/05/27
A natural small molecule isoginkgetin alleviates hypercholesterolemia and atherosclerosis by targeting ACLY 期刊论文  OAI收割
THERANOSTICS, 2025, 卷号: 15, 期号: 10, 页码: 4325-4344
作者:  
Zhang, Zhidan;  Chen, Meijie;  Xu, Yitong;  Wang, Zhihua;  Liu, Zhenghong
  |  收藏  |  浏览/下载:0/0  |  提交时间:2025/06/23
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics of BGT-002, a Novel ATP-Citrate Lyase Inhibitor, in Healthy Chinese Subjects 期刊论文  OAI收割
DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 卷号: 19, 页码: 1783-1794
作者:  
Liu, Yun;  Yu, Chengyin;  Zhang, Yifan;  Xie, Zhifu;  Wang, Yating
  |  收藏  |  浏览/下载:2/0  |  提交时间:2025/04/24
Single Amine or Guanidine Modification on Norvancomycin and Vancomycin to Overcome Multidrug-Resistance through Augmented Lipid II Binding and Increased Membrane Activity 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 22, 页码: 20639-20663
作者:  
Bian, Xiaolei;  Chen, Zhifu;  Li, Fang;  Xie, Yuanyuan
  |  收藏  |  浏览/下载:11/0  |  提交时间:2024/12/11
Discovery of Alkyl Conjugated Diene Diacids as Novel ACLY Inhibitors 期刊论文  OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 11, 页码: 3476-3489
作者:  
Cheng, Tingting
  |  收藏  |  浏览/下载:9/0  |  提交时间:2025/02/28
The Effect of Impact Load on the Atomistic Scale Fracture Behavior of Nanocrystalline bcc Iron 期刊论文  OAI收割
NANOMATERIALS, 2024, 卷号: 14, 期号: 4, 页码: 11
作者:  
Zhao, Zhifu;  Wang, Zhen;  Bie, Yehui;  Liu, Xiaoming;  Wei, Yueguang
  |  收藏  |  浏览/下载:19/0  |  提交时间:2024/04/02
Fast Radio Bursts: Electromagnetic Counterparts to Extreme Mass-ratio Inspirals 期刊论文  OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2023, 卷号: 956, 期号: 1, 页码: L2
作者:  
Li, Rui-Nan;  Zhao, Zhen-Yin;  Gao, Zhifu;  Wang, Fa-Yin
  |  收藏  |  浏览/下载:0/0  |  提交时间:2024/01/10
Chemical Weathering Intensity as a Reliable Indicator for Southwest Summer Monsoon Reconstruction: Evidence From Clay Minerals of Qionghai Lake Sediments Since the Last Glacial Maximum 期刊论文  OAI收割
GEOCHEMISTRY GEOPHYSICS GEOSYSTEMS, 2023, 卷号: 24, 期号: 7, 页码: 17
作者:  
Yu, Xiaoli;  Wang, Gen;  Zhang, Ting;  Ma, Xueyun;  Zhang, Xiaomei
  |  收藏  |  浏览/下载:29/0  |  提交时间:2024/01/02
Influence of the Late Ordovician-Early Silurian Paleoenvironment and Related Geological Processes on the Organic Matter Accumulation and Carbon Isotope Excursion 期刊论文  OAI收割
PALEOCEANOGRAPHY AND PALEOCLIMATOLOGY, 2023, 卷号: 38, 期号: 7, 页码: 22
作者:  
Zhang, Pengyuan;  Wang, Yongli;  Wei, Zhifu;  Wang, Gen;  Zhang, Ting
  |  收藏  |  浏览/下载:18/0  |  提交时间:2024/01/02