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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
地球环境研究所 [14]
上海药物研究所 [11]
地理科学与资源研究所 [4]
青藏高原研究所 [2]
化学研究所 [2]
过程工程研究所 [2]
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OAI收割 [50]
内容类型
期刊论文 [50]
发表日期
2025 [2]
2024 [3]
2023 [3]
2022 [5]
2021 [4]
2020 [6]
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地理学::自然地理学 [2]
Chemistry [1]
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(+)-Borneol Enhances the Antiseizure Effects of Retigabine by both Pharmacokinetic and Pharmacodynamic Interaction
期刊论文
OAI收割
NEUROCHEMICAL RESEARCH, 2025, 卷号: 50, 期号: 3, 页码: 13
作者:
Xu, Haiyan
;
Wu, Zhidan
;
Wang, Pei
;
Gong, Jili
;
Qiu, Li
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/06/23
Epilepsy
Retigabine
(+)-Borneol
Synergistic interaction
KCNQ channels
Glycyrrhizic acid and patchouli alcohol in Huoxiang Zhengqi attenuate intestinal inflammation and barrier injury via regulating endogenous corticosterone metabolism mediated by 11β-HSD1
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 338, 页码: 17
作者:
Wang, Yangyang
;
Sun, Chuying
;
Cao, Yutang
;
Jiao, Tingying
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/12/16
Huoxiang Zhengqi
Glycyrrhizic acid
Patchouli alcohol
Inflammation
Intestinal barrier injury
11 beta-hydroxysteroid dehydrogenase 1
A Knowledge-Guided Spatio-Temporal Correlation Measure Considering Rules and Dependency Syntax for Knowledge Graph Adaptive Representation
期刊论文
OAI收割
TRANSACTIONS IN GIS, 2024, 卷号: N/A
作者:
Qiu, Qinjun
;
Li, Haiyan
;
Hu, Xinxin
;
Tian, Miao
;
Ma, Kai
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/01/17
dependent syntax
geographic information retrieval
geographic knowledge graph
knowledge-guided approach
spatio-temporal correlation
Discovery of Novel Pyrimidine-Based Derivatives as Nav1.2 Inhibitors with Efficacy in Mouse Models of Epilepsy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12912-12931
作者:
He, Guoxue
;
Zheng, Yueming
;
Chang, Shunzhen
;
Wang, Long
;
Yang, Xiaohao
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/09/26
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2024/03/25
Discovery of selective NaV1.8 inhibitors based on 5-chloro-2-(4,4-difluor- oazepan-1-yl)-6-methyl nicotinamide scaffold for the treatment of pain
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 12
作者:
Qin, Hui
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/10/17
Pain
Non-addictive analgesics
Na V 1
8-selective inhibitors
Bicyclic aromatic groups
Design, Synthesis and Bioactivity of [3.3.3]Propellane-Based Voltage-Gated Calcium Channel alpha 2 delta Subunit Ligands
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 6, 页码: 2226-2238
作者:
He Jinyan
;
Tian Fuyun
;
Wu Qingqing
;
Zheng Yueming
;
Chen Yuting
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/10/17
propellane
voltage-gated calcium channel
alpha 2 delta subunit
synthesis
bioactivity
structure-activity relationship
Nitrogen Significantly Affected N Cycling Functional Gene Abundances Compared with Phosphorus and Drought in an Alpine Meadow
期刊论文
OAI收割
AGRONOMY-BASEL, 2023, 卷号: 13, 期号: 4, 页码: 1041
作者:
Li, Haiyan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/01/04
differential response
drought
interaction effect
N cycling functional gene
nitrogen addition
phosphorus addition
Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel alpha 2 delta ligands for the treatment of chronic neuropathic pain
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2022, 页码: 26
作者:
Zhang, Yuanwen
;
Zheng, Yueming
;
Wu, Qingqing
;
Tian, Fuyun
;
Ma, Chuanjun
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2023/04/10
Voltage-gated calcium channel
alpha 2 delta subunit
gamma-aminobutyric acid
Mirogabalin
Neuropathic pain
Structure-activity relationship
Epilepsy phenotype and response to KCNQ openers in mice harboring the Kcnq2 R207W voltage-sensor mutation
期刊论文
OAI收割
NEUROBIOLOGY OF DISEASE, 2022, 卷号: 174, 页码: 10
作者:
Tian, Fuyun
;
Cao, Birong
;
Xu, Haiyan
;
Zhan, Li
;
Nan, Fajun
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/12/13
KCNQ2
Epilepsy
Mouse model
HN37 (pynegabine)