机构

• 上海药物研究所 [13]
• 地球化学研究所 [4]
• 遥感与数字地球研究所 [1]

采集方式

• OAI收割 [18]

内容类型

• 期刊论文 [18]

发表日期

• 2021 [2]
• 2020 [4]
• 2019 [1]
• 2018 [3]
• 2016 [1]
• 2007 [2]
• 更多

学科主题

• 环境地球化学 [1]

筛选

浏览/检索结果: 共18条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11 作者:  Fan, Shijie;  Yue, Liyan;  Wan, Wei;  Zhang, Yuanyuan;  Zhang, Bidong   |  收藏  |  浏览/下载：113/0  |  提交时间：2021/12/16 covalent modification  probes  proteome  LC3  post-translational modification   DrugSpaceX: a large screenable and synthetically tractable database extending drug space 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2021, 卷号: 49, 期号: D1, 页码: D1170-D1178 作者:  Yang, Tianbiao;  Li, Zhaojun;  Chen, Yingjia;  Feng, Dan;  Wang, Guangchao   |  收藏  |  浏览/下载：62/0  |  提交时间：2021/05/24 Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737 作者:  Li, Xutong;  Li, Zhaojun;  Wu, Xiaolong;  Xiong, Zhaoping;  Yang, Tianbiao   |  收藏  |  浏览/下载：45/0  |  提交时间：2020/12/21 Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737 作者:  Li, Xutong;  Li, Zhaojun;  Wu, Xiaolong;  Xiong, Zhaoping;  Yang, Tianbiao   |  收藏  |  浏览/下载：33/0  |  提交时间：2020/12/21 TransformerCPI: improving compound-protein interaction prediction by sequence-based deep learning with self-attention mechanism and label reversal experiments 期刊论文  OAI收割 BIOINFORMATICS, 2020, 卷号: 36, 期号: 16, 页码: 4406-4414 作者:  Chen, Lifan;  Tan, Xiaoqin;  Wang, Dingyan;  Zhong, Feisheng;  Liu, Xiaohong   |  收藏  |  浏览/下载：31/0  |  提交时间：2021/05/24 Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion 期刊论文  OAI收割 ADVANCED SCIENCE, 2020, 页码: 13 作者:  Sun, Zhongya;  Zhang, Hao;  Zhang, Yuanyuan;  Liao, Liping;  Zhou, Wen   |  收藏  |  浏览/下载：87/0  |  提交时间：2020/07/01 anti-metastasis activities  crystal structures  inhibitors  novel pockets  rho family proteins   KinomeX: a web application for predicting kinome-wide polypharmacology effect of small molecules 期刊论文  OAI收割 BIOINFORMATICS, 2019, 卷号: 35, 期号: 24, 页码: 5354-5356 作者:  Li, Zhaojun;  Li, Xutong;  Liu, Xiaohong;  Fu, Zunyun;  Xiong, Zhaoping   |  收藏  |  浏览/下载：241/0  |  提交时间：2020/07/01 Artificial intelligence in drug design 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2018, 卷号: 61, 期号: 10, 页码: 1191-1204 作者:  Zhong, Feisheng;  Xing, Jing;  Li, Xutong;  Liu, Xiaohong;  Fu, Zunyun   |  收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08 drug design  artificial intelligence  deep learning  QSAR  ADME/T   Computational chemical biology and drug design: Facilitating protein structure, function, and modulation studies 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2018, 卷号: 38, 期号: 3, 页码: 914-950 作者:  Zheng, Mingyue;  Zhao, Jihui;  Cui, Chen;  Fu, Zunyun;  Li, Xutong   |  收藏  |  浏览/下载：58/0  |  提交时间：2019/01/08 ADMET  chemical biology  drug design  in silico  lead optimization  molecular dynamics  polypharmacology  virtual screening   artificialintelligenceindrugdesign 期刊论文  OAI收割 sciencechinalifesciences, 2018, 卷号: 61, 期号: 10, 页码: 1191 作者:  Zhong Feisheng;  Xing Jing;  Li Xutong;  Liu Xiaohong;  Fu Zunyun   |  收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 PROTEIN-PROTEIN-INTERACTION  MACHINE LEARNING-METHODS  COMPUTATIONAL METHODS  MOLECULAR-PROPERTIES  INTERACTION NETWORKS  NEURAL-NETWORKS  PREDICTION  DOCKING  DISCOVERY  PERMEABILITY  drug design  artificial intelligence  deep learning  QSAR  ADME/T