机构

• 上海药物研究所 [13]
• 金属研究所 [8]
• 高能物理研究所 [5]
• 武汉物理与数学研究所 [2]
• 兰州化学物理研究所 [2]

采集方式

• OAI收割 [30]

内容类型

• 期刊论文 [28]
• 专利 [1]
• 会议论文 [1]

发表日期

• 2024 [4]
• 2023 [4]
• 2022 [4]
• 2019 [3]
• 2018 [2]
• 2017 [3]
• 更多

学科主题

• Materials ... [1]
• Metallurgy... [1]

筛选

浏览/检索结果: 共30条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 330, 页码: 12 作者:  Wang, Long;  Hao, Haishuang;  Meng, Xianhua;  Zhang, Wenbo;  Zhang, Yin   |  收藏  |  浏览/下载：113/0  |  提交时间：2024/11/05 HJ-69  Zanthoxylum bungeanum  Isoquinoline alkaloid  Nav  Kv  Inflammatory pain   Discovery of Novel Pyrimidine-Based Derivatives as Nav1.2 Inhibitors with Efficacy in Mouse Models of Epilepsy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12912-12931 作者:  He, Guoxue;  Zheng, Yueming;  Chang, Shunzhen;  Wang, Long;  Yang, Xiaohao   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/09/26 Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2024, 页码: 29 作者:  Zhou, Xiaoyu;  Zhao, Cheng;  Xu, Haiyan;  Xu, Yixiang;  Zhan, Li   |  收藏  |  浏览/下载：33/0  |  提交时间：2024/03/25 A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels 期刊论文  OAI收割 Journal of Ethnopharmacology, 2024, 卷号: 330, 期号: 2024, 页码: 118218 作者:  Yang JL(杨军丽);  Wang L(王龙);  Hao HS(郝寒霜);  Meng XH(孟宪华);  Zhang WB(张文博)   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/12/13 Ligand activation mechanisms of human KCNQ2 channel 期刊论文  OAI收割 Nature communications, 2023, 卷号: 14, 期号: 1, 页码: 6632 作者:  Ma, Demin;  Zheng, Yueming;  Li, Xiaoxiao;  Zhou, Xiaoyu;  Yang, Zhenni   |  收藏  |  浏览/下载：39/0  |  提交时间：2024/03/26 Discovery of selective NaV1.8 inhibitors based on 5-chloro-2-(4,4-difluor- oazepan-1-yl)-6-methyl nicotinamide scaffold for the treatment of pain 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 12 作者:  Qin, Hui;  Wei, Aihuan;  Wang, Yunqi;  Wang, Linlin;  Xu, Haiyan   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/10/17 Pain  Non-addictive analgesics  Na V 1  8-selective inhibitors  Bicyclic aromatic groups   Design, Synthesis and Bioactivity of [3.3.3]Propellane-Based Voltage-Gated Calcium Channel alpha 2 delta Subunit Ligands 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 6, 页码: 2226-2238 作者:  He Jinyan;  Tian Fuyun;  Wu Qingqing;  Zheng Yueming;  Chen Yuting   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/10/17 propellane  voltage-gated calcium channel  alpha 2 delta subunit  synthesis  bioactivity  structure-activity relationship   Naphthylisoquinoline alkaloids,a new structural template inhibitor of Navl.7 sodium channel 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 9, 页码: 1768 作者:  Wang Qiaoqiao;  Wang Long;  Zhang Wenbo;  Tang Chunping;  Chen Xueqin   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/12/08 Navl.7 channel  naphthylisoquinolines  Ancistrocladus tectorius  dorsal root ganglion neurons  formalin-induced mouse inflammatory pain model  analgesics   Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel alpha 2 delta ligands for the treatment of chronic neuropathic pain 期刊论文  OAI收割 MEDICINAL CHEMISTRY RESEARCH, 2022, 页码: 26 作者:  Zhang, Yuanwen;  Zheng, Yueming;  Wu, Qingqing;  Tian, Fuyun;  Ma, Chuanjun   |  收藏  |  浏览/下载：38/0  |  提交时间：2023/04/10 Voltage-gated calcium channel  alpha 2 delta subunit  gamma-aminobutyric acid  Mirogabalin  Neuropathic pain  Structure-activity relationship   具有抗癫痫活性的化合物及其在制备抗癫痫药物中的应用 专利  OAI收割 专利号: ZL202111341217.5, 申请日期: 2022-09-06, 作者:  杨军丽;  高召兵;  郑月明;  孟宪华;  许海燕   |  收藏  |  浏览/下载：20/0  |  提交时间：2022/11/30