机构

• 上海药物研究所 [9]
• 上海神经科学研究所 [1]
• 海洋研究所 [1]

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [10]
• CNKI期刊论文 [1]

发表日期

• 2023 [1]
• 2022 [2]
• 2020 [5]
• 2017 [1]
• 2016 [1]
• 2012 [1]
• 更多

学科主题

• Neuroscien... [1]

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region 期刊论文  OAI收割 JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 2, 页码: 107942 作者:  Jiang, Hao;  Zu, Shijia;  Lu, Yu;  Sun, Zhongya;  Adeerjiang, Akejiang   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/03/27 Small GTPases  Crystal structures of RhoA  Dynamics of switch II  Molecular dynamics simulations  Allosteric pocket   The discovery of a non-competitive GOT1 inhibitor, hydralazine hydrochloride, via a coupling reaction-based high-throughput screening assay 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 73, 页码: 6 作者:  Wu, Qiqi;  Sun, Zhongya;  Chen, Zhifeng;  Liu, Jingqiu;  Ding, Hong   |  收藏  |  浏览/下载：72/0  |  提交时间：2022/08/30 Glutamate oxaloacetate transaminase 1  Inhibitor  Hydralazine hydrochloride  High -throughput screening   Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 2, 页码: 470 作者:  Li Wen;  Liao Liping;  Song Ning;  Liu Yanjun;  Ding Yiluan   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/05/22 glyceraldehyde 3-phosphate dehydrogenase  1  2  3  4  6-penta-O-galloyl-β-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu   |  收藏  |  浏览/下载：34/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia   Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5 作者:  Zhang, Bin;  Liao, Liping;  Wu, Fan;  Zhang, Fengcai;  Sun, Zhongya   |  收藏  |  浏览/下载：54/0  |  提交时间：2021/05/24 SMYD2 inhibitors  Thermal shift assay  Structure-activity relationships   Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11 作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan   |  收藏  |  浏览/下载：42/0  |  提交时间：2020/12/24 In silico screening  Drug design  CBP  Bromodomain  Inhibitor  Acute Myeloblastic Leukemia   Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion 期刊论文  OAI收割 ADVANCED SCIENCE, 2020, 页码: 13 作者:  Sun, Zhongya;  Zhang, Hao;  Zhang, Yuanyuan;  Liao, Liping;  Zhou, Wen   |  收藏  |  浏览/下载：86/0  |  提交时间：2020/07/01 anti-metastasis activities  crystal structures  inhibitors  novel pockets  rho family proteins   A Sphingosine-1-Phosphate Modulator Ameliorates Polycystic Kidney Disease in Han:SPRD Rats 期刊论文  OAI收割 AMERICAN JOURNAL OF NEPHROLOGY, 2020, 卷号: 51, 期号: 1, 页码: 1-10 作者:  Li, Xin;  Wu, Ming;  Chen, Limin;  Lu, Junyan;  Li, Guo   |  收藏  |  浏览/下载：54/0  |  提交时间：2020/07/01 FTY720  Sphingosine-1-phosphate  Cordyceps sinensis  Autosomal dominant polycystic kidney disease  Inflammation   Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 9, 页码: 2003-2009 作者:  Sun, Zhongya;  Zhang, Hao;  Chen, Zhifeng;  Xie, Yiqian;  Jiang, Hao   |  收藏  |  浏览/下载：104/0  |  提交时间：2019/01/08 BRD4 inhibitor  High-throughput screening  Crystallography   近60年来南黄海沉积物高分辨率敏感粒级对东亚冬季风的响应 CNKI期刊论文  OAI收割 2016 作者:  高星华;  李广雪;  张海啟;  Dada Olusegun A;  刘世东   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/12/18 南黄海泥质区  敏感粒级  东亚季风  高分辨率  长江输沙