中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [27]
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期刊论文 [173]
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Guiding precision medicine strategy for intravenous ginsenosides via pharmacokinetic-informed bioinformatic approaches: a study on XueShuanTong
期刊论文
OAI收割
PHYTOMEDICINE, 2025, 卷号: 143, 页码: 18
作者:
Jia, Wei-Wei
;
Tian, Nan-Nan
;
Song, Zi-Jing
;
Lan, Xiao-Fang
;
Yang, Xi-He
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/08/20
Precision medicine
Physiologically based pharmacokinetic model
Ginsenoside
Albumin-facilitated dissociation
Drug interaction
Drug transporter
Hepatic impairment
Quantitative Proteomic Study Reveals Amygdalin Alleviates Liver Fibrosis Through Inhibiting mTOR/ PDCD4/JNK Pathway in Hepatic Stellate Cells
期刊论文
OAI收割
DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 卷号: 19, 页码: 3735-3749
作者:
Huang, Hui
;
Ru, Su-Jie
;
Chen, Jia-Mei
;
Liu, Wei
;
Fang, Shan-Hua
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/07/25
amygdalin
PDCD4
HSC activation
proteomics
Characterization of regolith-hosted rare earth element deposits using reflectance spectroscopy: Framework towards an efficient and reliable field exploration tool
期刊论文
OAI收割
JOURNAL OF GEOCHEMICAL EXPLORATION, 2024, 卷号: 267, 页码: 19
作者:
Li, Martin Yan Hei
;
Liu, Jiacheng
;
Tan, Wei
;
Zhou, Jia-Xi
;
Zhou, Mei-Fu
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2025/04/01
Rare earth elements
Regolith-hosted deposits
Reflectance spectroscopy
VNIR-SWIR spectroscopy
Clay minerals
Weathering
Mass balance, metabolism, and pharmacokinetics of [
14
C]amdizalisib, a clinical-stage novel oral selective PI3Kδ inhibitor for the treatment of non-hodgkin's lymphoma, in healthy Chinese volunteers
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Zhao, Chun-Yang
;
Zhang, Li-Jun
;
Sun, Chan
;
Yu, Cheng-Yin
;
Wang, Jian
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2025/01/06
amdizalisib
PI3K delta kinase
metabolism
mass balance
metabolite identification
pharmacokinetics
safety
Circulating metabolites of
Borneolum syntheticum
(Bingpian) ameliorate atherosclerosis in ApoE
-/-
mice via inhibiting macrophage foam-cell formation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 18
作者:
He, Rong-rong
;
Ma, Chuan-rui
;
He, Xin
;
Dong, Yan-xi
;
Li, Hui
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2024/11/26
Borneolum syntheticum
Bingpian
borneol
isoborneol
metabolism
atherosclerosis
19
F qNMR based pharmacokinetics, metabolism and mass balance studies of SARS-CoV-2-3CL protease inhibitor simnotrelvir (SIM0417) in humans
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Wang, Ze-yu
;
Ren, Yong-mei
;
Hu, Shu-wei
;
Zhang, Nai-xia
;
Dong, Meng-xiao
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/11/05
COVID-19
simnotrelvir
F-19 qNMR
pharmacokinetics
metabolism
mass balance.
Heterozygous variants in USP25 cause genetic generalized epilepsy
期刊论文
OAI收割
BRAIN, 2024, 页码: 16
作者:
Fan, Cui-Xia
;
Liu, Xiao-Rong
;
Mei, Dao-Qi
;
Li, Bing-Mei
;
Li, Wen-Bin
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2024/10/09
genetic generalized epilepsy
USP25
gain of function
loss of function
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2024/09/10
Luteolin-7-diglucuronide, a novel PTP1B inhibitor, ameliorates hepatic stellate cell activation and liver fibrosis in mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Tang, Bi-xi
;
Zhang, Yong
;
Sun, Dan-dan
;
Liu, Qin-yi
;
Li, Cong
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2024/09/26
liver fibrosis
phytochemical
luteolin 7-diglucuronide
HSC activation
PTP1B
Synergistic antibacterial and antifouling wound dressings: Integration of photothermal-activated no release and zwitterionic surface modification
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2024, 卷号: 657, 页码: 11
作者:
Li, Yan-Hong
;
Huang, Zeng-Jin
;
Zhang, Jia-Qi
;
Ye, Meng -Nan
;
Jun, Mei
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/11/17
Nitric oxide
Zwitterionic wound dressing
Bacterial infections
Biofilm