中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [168]
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期刊论文 [372]
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Bicyclic polyprenylated acylphloroglucinol-related meroterpenoids as potent DRAK2 inhibitors from
Hypericum patulum
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 232, 页码: 10
作者:
Huang, Jin-Chang
;
Jia, Xin-Yu
;
Lv, Yi-Fan
;
Xu, Hong-Hong
;
Han, Ming
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Hypericum patulum
Hypericaceae
Meroterpenoids
Hyperpatins A-H
Death-associated protein kinase-related
apoptosis-inducing kinase 2
Glucose-stimulated insulin secretion
Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13
作者:
Tang, Mingze
;
Zhou, Xuan
;
Shen, Qianqian
;
Fang, Chen
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/08/22
Receptor -interacting protein kinase 1
Histone deacetylases
Inhibitor
Molecular dynamics (MD) simulation
ADMET analysis
Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 16
作者:
An, Yuxiang
;
Peng, Xia
;
Wang, Tianchen
;
Liu, Kaiyuan
;
Feng, Dazhi
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/25
inhibitor
pharmacokinetic study
pyridazin-4-one
receptor-interacting protein kinase 1
selectivity
Chiral Nanostructured Ag Films for Multicarbon Products from CO
2
Electroreduction
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 卷号: 146
作者:
Zhang, Wanning
;
Ai, Jing
;
Ouyang, Tianwei
;
Yu, Lu
;
Liu, Aokun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/11/20
13,14-seco
seco
withaphysalins from
Physalis
minima
and their inhibitory effects on NLRP3 inflammasome activation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 151, 页码: 12
作者:
Hu, Bintao
;
Peng, Xia
;
Tang, Chunping
;
Geng, Meiyu
;
Yao, Sheng
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/09/26
Physalis minima
NLRP3
Anti-inflammatory
13,14-seco withaphysalin
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/09/10
Design, synthesis, and structure-activity relationship studies of 6,7-dihydro-5
H
-pyrrolo[1,2-
b
][1,2,4]triazole derivatives as necroptosis inhibitors
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2024, 卷号: 15, 期号: 7, 页码: 2514-2526
作者:
Jin, Zechen
;
Dai, Yang
;
Ji, Yinchun
;
Peng, Xia
;
Duan, Wenhu
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/08/20
Discovery and optimization of 3-(indolin-5-yloxy)pyridin-2-amine derivatives as potent necroptosis inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 21
作者:
Lan, Yaohan
;
Ji, Yinchun
;
Peng, Xia
;
Duan, Wenhu
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/08/22
autoimmune disease
necroptosis inhibitor
pharmacokinetic profile
receptor interacting protein kinase 1 (RIPK1)
structural optimization
Hyperlanins A and B, Two Highly Rearranged Meroterpenoids from
Hypericum lancasteri
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2024, 页码: 7
作者:
You, Jin-Qiu
;
Jin, Yun-Qi
;
Li, Meng-Yu
;
Zhang, Bo-Chao
;
Sun, Xin-Yu
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/06/27
Natural products
Hypericum lancasteri
Meroterpenoids
Structure elucidation
Inflammation
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer