中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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高能物理研究所 [139]
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期刊论文 [318]
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Strategies reimagined: SDG-driven solutions for combating global desertification
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2026, 卷号: 123, 期号: 1, 页码: e2515470123
作者:
Wang, Xunming
;
Geng, Xin
;
Sun, Fubao
;
Han, Mengyao
;
Chen, Fahu
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2026/03/16
desertification
sustainable development goal
policy rectification
climate-economic system
Rational engineering of degradation tail-driven CELMoD-antibody conjugates for precision malignancy therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 12, 页码: 6510-6528
作者:
Guo, Yu
;
Song, Yi
;
Wang, Hanlin
;
Lu, Yang
;
Zhang, Jingyu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2026/01/29
Degrader-antibody conjugate
Antibody-drug conjugate
Cereblon E3 ligase modulator
Immunomodulatory drug
Molecular glue
Targeted protein degradation
Multiple myeloma
Hematologic malignancy
Modular PROTAC/IMiD Bifunctional Molecule Design for the Degradation of Synergistic Targets in the Treatment of Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 20, 页码: 21249-21281
作者:
Jin, Yuheng
;
Liao, Xueyan
;
Zhang, Jingyu
;
Duan, Haiting
;
Xu, Ran
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/12/04
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Discovery of a Selective and Potent BCL6 PROTAC with Efficacious Antiproliferative Activity for the Treatment of Diffuse Large B-Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 19, 页码: 20180-20206
作者:
Yu, Xiaoli
;
Liao, Xueyan
;
Zhang, Jingyu
;
Wang, Hanlin
;
Li, Xian
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/12/04
Discovery of a ubiquitin-specific protease 10 inhibitor with high binding affinity promoting cell apoptosis via down-regulated CDK4 for the treatment of hepatocellular carcinoma
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 17
作者:
Lu, Yang
;
Wang, Wentao
;
Yuan, Cheng
;
Luo, Mengxin
;
Wang, Peipei
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/12/04
HCC
USP10
Deubiquitination
Binding affinity
CDK4
Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679
作者:
Jin, Yuheng
;
Qi, Xuxin
;
Yu, Xiaoli
;
Cheng, Xirui
;
Chen, Boya
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2025/06/23
HDAC7
PROTAC
Selectivity
Hematologic malignancies
Non-enzymatic function
Unbiased Detection of Warming Trends Through Advanced Integration of Satellite and Reanalysis Air Temperatures
期刊论文
OAI收割
IEEE JOURNAL OF SELECTED TOPICS IN APPLIED EARTH OBSERVATIONS AND REMOTE SENSING, 2025, 卷号: 18, 页码: 24924-24935
作者:
Wang, Che
;
He, Min
;
Lu, Ning
;
Qin, Jun
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/11/17
Air temperatures
data assimilation
moderate-resolution imaging spectroradiometer (MODIS)
reanalysis
unbiased detection
warming trends
Air temperatures
data assimilation
moderate-resolution imaging spectroradiometer (MODIS)
reanalysis
unbiased detection
warming trends
Impact of Rising Compound Drought and Heatwaves on Vegetation in Global Drylands
期刊论文
OAI收割
IEEE JOURNAL OF SELECTED TOPICS IN APPLIED EARTH OBSERVATIONS AND REMOTE SENSING, 2025, 卷号: 18, 页码: 24509-24517
作者:
Wang, Che
;
Sun, Xupeng
;
Lu, Ning
;
Qin, Jun
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/11/17
Heating systems
Vegetation mapping
Soil moisture
Droughts
Indexes
Market research
Vegetation
Predictive models
Monitoring
Temperature distribution
Drylands
heatwaves
interpretable machine learning
solar-induced fluorescence (SIF)
Chiral Nanostructured Ag Films for Multicarbon Products from CO
2
Electroreduction
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 卷号: 146
作者:
Zhang, Wanning
;
Ai, Jing
;
Ouyang, Tianwei
;
Yu, Lu
;
Liu, Aokun
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2024/11/20