中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [78]
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期刊论文 [534]
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Therapeutic potential and pharmacological mechanisms of Traditional Chinese Medicine in gout treatment
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 21
作者:
Guo, Jing-wen
;
Lin, Guo-qiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
gout
hyperuricemia
gouty arthritis
Traditional Chinese Medicine
TCM formula
Chinese herb
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Zhai, Lin-hui
;
Jia, Xing-long
;
Chen, Yu-lu
;
Liu, Mu-yin
;
Zhang, Jing-dan
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2024/12/25
colchicine
MLN4924
multi-omics analysis
phosphoproteomics
ubiquitinomics
kinase inhibitor
Structure-guided design and photochemical synthesis of new carbamo (dithioperoxo)thioates with improved potencies to SARS-CoV-2 3CLpro
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 114, 页码: 9
作者:
Yin, De-Hang
;
Xin, Jie
;
Chen, Shizhao
;
Li, Shuai-Shuai
;
Li, Zi-Ying
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/12/11
SARS-CoV-2
Disulfiram
Carbamo(dithioperoxo)thioates
Photochemistry
3CL pro
Mass balance, metabolism, and pharmacokinetics of [
14
C]amdizalisib, a clinical-stage novel oral selective PI3Kδ inhibitor for the treatment of non-hodgkin's lymphoma, in healthy Chinese volunteers
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Zhao, Chun-Yang
;
Zhang, Li-Jun
;
Sun, Chan
;
Yu, Cheng-Yin
;
Wang, Jian
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/01/06
amdizalisib
PI3K delta kinase
metabolism
mass balance
metabolite identification
pharmacokinetics
safety
Neglected plants of
Prunus
L. (Rosaceae) in East China
期刊论文
OAI收割
PHYTOTAXA, 2024, 卷号: 669, 期号: 1, 页码: 13-24
作者:
Li, Jun-Ping
;
Chen, Feng
;
Xie, Wen-Yuan
;
Wang, Jun-Feng
;
Mao, Li-Mi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/03/28
Prunus
taxonomy
new species
new variety
East China
Tofacitinib prevents depressive-like behaviors through decreased hippocampal microgliosis and increased BDNF levels in both LPS-induced and CSDS-induced mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Gao, Ya-nan
;
Pan, Kai-jun
;
Zhang, Yong-mei
;
Qi, Ying-bei
;
Chen, Wen-gang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/11/05
tofacitinib
depression
JAK-STAT pathway
microgliosis
synaptic defects
Global marine microbial diversity and its potential in bioprospecting
期刊论文
OAI收割
NATURE, 2024, 页码: 27
作者:
Chen, Jianwei
;
Jia, Yangyang
;
Sun, Ying
;
Liu, Kun
;
Zhou, Changhao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/10/21
FAST Detection of OH Emission in the Carbon-rich Planetary Nebula NGC 7027
期刊论文
OAI收割
The Astrophysical Journal, 2024, 卷号: 972, 期号: 1
作者:
Ouyang,Xu-Jia
;
Zhang,Yong
;
Zhang,Chuan-Peng
;
Jiang,Peng
;
Nakashima,Jun-ichi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/03
Heterozygous variants in USP25 cause genetic generalized epilepsy
期刊论文
OAI收割
BRAIN, 2024, 页码: 16
作者:
Fan, Cui-Xia
;
Liu, Xiao-Rong
;
Mei, Dao-Qi
;
Li, Bing-Mei
;
Li, Wen-Bin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/10/09
genetic generalized epilepsy
USP25
gain of function
loss of function