中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [20]
昆明植物研究所 [12]
近代物理研究所 [9]
合肥物质科学研究院 [6]
广州地球化学研究所 [5]
高能物理研究所 [5]
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期刊论文 [106]
专著章节/文集论文 [1]
会议论文 [1]
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2025 [1]
2024 [2]
2023 [4]
2022 [7]
2021 [23]
2020 [9]
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Plant Scie... [3]
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Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect
Heterozygous variants in USP25 cause genetic generalized epilepsy
期刊论文
OAI收割
BRAIN, 2024, 页码: 16
作者:
Fan, Cui-Xia
;
Liu, Xiao-Rong
;
Mei, Dao-Qi
;
Li, Bing-Mei
;
Li, Wen-Bin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/10/09
genetic generalized epilepsy
USP25
gain of function
loss of function
Liquid-level response measurement using high-speed videogrammetry with robust multiple sphere tracking
期刊论文
OAI收割
MEASUREMENT, 2024, 卷号: 228, 页码: 18
作者:
Tong, Xiaohua
;
Shi, Haibo
;
Ye, Zhen
;
Chen, Peng
;
Liu, Ziqi
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/05/14
High -speed videogrammetry
Liquid-level response measurement
Spherical target tracking
Shaking table test
Prevalence and clinical correlates of abnormal glucose metabolism in young, first- episode and medication-naive outpatients with major depressive disorder
期刊论文
OAI收割
PSYCHIATRY RESEARCH, 2023, 卷号: 325, 页码: 8
作者:
Chen, Yi-Huan
;
Wang, Hua-Ning
;
Lang, Xiao-E
;
Zhang, Xiang -Yang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/09
Abnormal glucose metabolism
Medication -naive
Major depressive disorder
Young
First-episode
Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9
作者:
Li, Hua-ying
;
Chen, Yi-li
;
Deng, Xiang-nan
;
Li, Huan-huan
;
Tan, Jie
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2023/10/17
cancer immunotherapy
B7-H3
PD-L1
bispecific antibodies
VHH
antibody-dependent cell-mediated cytotoxicity (ADCC)
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
Chemical Constituents of Primulina eburnea (Gesneriaceae) and Their Cytotoxic Activities
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2023
作者:
Yang,Li-Yuan
;
Yi,Ping
;
Chen,Jun-Lei
;
Li,Yu-Huan
;
Qiu,Jue-Lin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/07/10
Primulina eburnea
triterpenes
flavonoids
phenylethanoid glycosides
cytotoxic activity
GLUCOSIDES
LEAVES
CELL
Absorption, distribution, metabolism, and excretion of [C-14]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2022, 页码: 12
作者:
Li, Xin-mei
;
Zheng, Yuan-dong
;
Zhang, Yi-fan
;
Huan, Xia-juan
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/12/13
[C-14]Mefuparib
Mefuparib (CVL218)
Blood-brain barrier
Mass balance
Tissue distribution
GastroPlus simulation
Pharmacokinetics, mass balance, and metabolism of [C-14]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13
作者:
He, Yi-fei
;
Liu, Yin
;
Yu, Jing-hua
;
Cheng, Huan
;
Odilov, Abdullajon
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/08/16
TPN171
[C-14]TPN171
PDE5 inhibitor
pulmonary arterial hypertension
healthy volunteers
pharmacokinetics
metabolite identification
mass balance
JUNO physics and detector
期刊论文
OAI收割
PROGRESS IN PARTICLE AND NUCLEAR PHYSICS, 2022, 卷号: 123, 页码: 51
作者:
  |  
收藏
  |  
浏览/下载:132/0
  |  
提交时间:2022/04/11
JUNO
neutrino physics
neutrino detector