中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [31]
上海生物化学与细胞... [10]
海洋研究所 [8]
南海海洋研究所 [5]
天津工业生物技术研究... [5]
金属研究所 [4]
更多
采集方式
OAI收割 [104]
iSwitch采集 [5]
内容类型
期刊论文 [105]
会议论文 [3]
CNKI期刊论文 [1]
发表日期
2025 [5]
2024 [14]
2023 [8]
2022 [13]
2021 [8]
2020 [6]
更多
学科主题
Biotechnol... [3]
Biochemist... [2]
Biochemist... [1]
Biochemist... [1]
Endocrinol... [1]
Engineerin... [1]
更多
筛选
浏览/检索结果:
共109条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Quantification of serum daratumumab in multiple myeloma patients by LC-MS/MS, comparison with ELISA
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 255, 页码: 7
作者:
Li, Weiqiang
;
Tian, Zhuoran
;
Yu, Xiong
;
Xu, Hongyu
;
Huang, Fang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/02/28
Multiple myeloma
Daratumumab
LC-MS/MS
Surrogate peptide
Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13
作者:
Wu, Feifei
;
Li, Huiyu
;
Li, Weiqiang
;
Zhang, Laishun
;
An, Qi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/04/01
Optimization
Hematopoietic progenitor kinase 1
Inhibitor
Cancer immunotherapy
Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel
Hs
ClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:
Sun, Mingyang
;
Chen, Beijing
;
Teng, Dan
;
Zhao, Hongshen
;
Liao, Yilie
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/01
PEGylation of Dipeptide Linker Improves Therapeutic Index and Pharmacokinetics of Antibody-Drug Conjugates
期刊论文
OAI收割
BIOCONJUGATE CHEMISTRY, 2025, 页码: 11
作者:
Long, Jing
;
Shao, Ting
;
Wang, Yongmei
;
Chen, Tianzhi
;
Chen, Yuning
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
Simultaneous Quantification of Total Antibody and Conjugated Payload for DS001 in Rat Serum Using a Hybrid Immuno-Capture LC-MS/MS
期刊论文
OAI收割
AAPS JOURNAL, 2025, 卷号: 27, 期号: 1, 页码: 13
作者:
Yu, Xiong
;
Li, Weiqiang
;
Huang, Wensi
;
Xiao, Bo
;
Long, Jing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
ADC
LC-MS/MS
payload
simultaneous quantification
total antibody
Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/11/26
Triple-negative breast cancer
Targeting transcription regulation
Orally bioavailable degrader
PROTAC
Cyclin-dependent Kinase 9
The seasonal evolution of the Yellow Sea Cold Water Mass Circulation: Roles of fronts, thermoclines, and tidal rectification
期刊论文
OAI收割
OCEAN MODELLING, 2024, 卷号: 190, 页码: 15
作者:
Hu, Yibo
;
Yu, Fei
;
Si, Guangcheng
;
Sun, Fan
;
Liu, Xingchuan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/09/02
Circulation
Yellow Sea Cold Water Mass
Front
Thermocline
Tidal rectification
Radioactive ADME Demonstrates ARV-110's High Druggability Despite Low Oral Bioavailability
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 15
作者:
He, Yifei
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/09/26
Discovery of Orally Bioavailable and Potent CDK9 Inhibitors for Targeting Transcription Regulation in Triple-Negative Breast Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 12, 页码: 10035-10056
作者:
Wang, Wen-Jing
;
Gao, Lixin
;
Wang, Simei
;
Huang, Wensi
;
Meng, Xin-Yu
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/08/20
A validated LC-MS/MS method for the quantitation of daratumumab in rat serum using rapid tryptic digestion without IgG purification and reduction
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 243, 页码: 8
作者:
Li, Weiqiang
;
Huang, Wensi
;
Yu, Xiong
;
Chen, Chong
;
Yuan, Yali
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/05/22
Daratumumab
LC-MS/MS
Surrogate peptide
Pharmacokinetics