中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
采集方式
OAI收割 [13]
内容类型
期刊论文 [12]
会议论文 [1]
发表日期
2022 [2]
2020 [1]
2019 [1]
2018 [1]
2017 [3]
2015 [2]
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Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 12, 页码: 22
作者:
Xie, Ningjie
;
Wang, Hong
;
Qin, Hua
;
Guo, Zitao
;
Xue, Hao
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/04/10
hepatic impairment
ezetimibe
active metabolites
phase II enzymes
transporters
first-pass metabolism
inhibitory bile acids
Mechanistic Study on the Species Differences in Excretion Pathway of HR011303 in Humans and Rats
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 809-818
作者:
Guo, Zitao
;
Liu, Mengling
;
Meng, Jian
;
Xue, Yaru
;
Huang, Qi
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/08/16
Drug interaction of ningetinib and gefitinib involving CYP1A1 and efflux transporters in non-small cell lung cancer patients
期刊论文
OAI收割
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 页码: 13
作者:
Liu, Lu
;
Wang, Qian
;
Xie, Cen
;
Xi, Ning
;
Guo, Zitao
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/12/24
drug–
drug interaction
gefitinib
ningetinib
transporters
Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 8, 页码: 843-853
作者:
Li, Xiuli
;
Sun, Jingchao
;
Guo, Zitao
;
Zhong, Dafang
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Pharmacokinetic Drug Interactions of Apatinib With Rifampin and Itraconazole
期刊论文
OAI收割
JOURNAL OF CLINICAL PHARMACOLOGY, 2018, 卷号: 58, 期号: 3, 页码: 347-356
作者:
Liu, Xiaoyun
;
Zhang, Yifan
;
Chen, Qian
;
Zhan, Yan
;
Wang, Quanren
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/01/08
apatinib
rifampin
itraconazole
drug-drug interaction
pharmacokinetics
Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2017, 卷号: 45, 期号: 6, 页码: 593-603
作者:
Kong, Fandi
;
Pang, Xiaoyan
;
Zhong, Kan
;
Guo, Zitao
;
Li, Xiuli
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2019/01/08
Impact of curcumin on the pharmacokinetics of rosuvastatin in rats and dogs based on the conjugated metabolites
期刊论文
OAI收割
XENOBIOTICA, 2017, 卷号: 47, 期号: 3, 页码: 267-275
作者:
Zhou, Xin
;
Zhang, Fangrong
;
Chen, Chang
;
Guo, Zitao
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Curcumin
drug-drug interaction
OAT
OATP
rosuvastatin
transporter
UREMIC TOXINS LIKELY BOOST THE PLASMA EXPOSURE OF MORINIDAZOLE CONJUGATED METABOLITES IN THE RENAL FAILURE PATIENTS
会议论文
OAI收割
作者:
Kong, Fandi
;
Pang, Xiaoyan
;
Zhong, Kan
;
Li, Xiuli
;
Guo, Zitao
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury
期刊论文
OAI收割
Drug metabolism and disposition: the biological fate of chemicals, 2015, 卷号: 43, 期号: 11, 页码: 1751-9
作者:
Li, Xiuli
;
Zhong, Kan
;
Guo, Zitao
;
Zhong, Dafang
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
potentialroleoforganicaniontransportingpolypeptide1b1oatp1b1intheselectivehepaticuptakeofhematoporphyrinmonomethyletherisomers
期刊论文
OAI收割
actapharmacologicasinica, 2015, 卷号: 000, 期号: 002, 页码: 268
作者:
Li Xiuli
;
Guo Zitao
;
Wang Yedong
;
Chen Xiaoyan
;
Liu Jia
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
血卟啉单甲醚
离子转运
异构体
摄取
肝脏
多肽
HEK293
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