中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
昆明植物研究所 [53]
上海药物研究所 [18]
西北高原生物研究所 [12]
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期刊论文 [228]
会议论文 [2]
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Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 277, 页码: 17
作者:
Zhuang, Zhen
;
Miao, Yu-Ling
;
Song, Shan-Shan
;
Leng, Guang-Tong
;
Zhang, Xiao-Fei
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/09/26
USP7 inhibitor
Structure-activity relationships
Anti-cancer
pyrrolo[2,3-d]pyrimidin-4-one
Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2024, 页码: 3
作者:
Lin, Ze-Min
;
Xiang, Mai
;
Wei, Wen-Hui
;
Fan, Shu-Hui
;
Chen, Li
  |  
收藏
  |  
浏览/下载:232/0
  |  
提交时间:2024/12/11
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/09/10
Large scale exploration reveals rare taxa crucially shape microbial assembly in alkaline lake sediments
期刊论文
OAI收割
NPJ BIOFILMS AND MICROBIOMES, 2024, 卷号: 10, 期号: 1, 页码: 13
作者:
Qiu, Zhiguang
;
He, Shuhang
;
Lian, Chun-Ang
;
Qiao, Xuejiao
;
Zhang, Qing
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/09/13
Skyway: Accelerate Graph Applications with a Dual-Path Architecture and Fine-Grained Data Management
期刊论文
OAI收割
JOURNAL OF COMPUTER SCIENCE AND TECHNOLOGY, 2024, 卷号: 39, 期号: 4, 页码: 871-894
作者:
Zou, Mo
;
Zhang, Ming-Zhe
;
Wang, Ru-Jia
;
Sun, Xian-He
;
Ye, Xiao-Chun
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/12/06
graph application
computer architecture
memory hierarchy
Diffusion and incidence of helium on tungsten surface
期刊论文
OAI收割
JOURNAL OF NUCLEAR MATERIALS, 2023, 卷号: 586
作者:
Wang, Jinlong
;
Guo, Jinmin
;
He, Bingling
;
Liu, Daping
;
Pan, Xin-Dong
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/11/10
Tungsten
Helium
Irradiation energy
Diffusion barrier
Depth distribution
Modeling of breaching parameters for debris flow dams
期刊论文
OAI收割
JOURNAL OF MOUNTAIN SCIENCE, 2023, 卷号: 20, 期号: 10, 页码: 2835-2851
作者:
Ruan, He-chun
;
Chen, Hua-yong
;
Chen, Xiao-qing
;
Zhao, Wan-yu
;
Chen, Jian-gang
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/03/14
Debris flow dams
Overtopping failure
Breaching parameters
Peak discharge
Flume experiment
A Catalog and Statistical Analysis for Magnetic Stars
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2023, 卷号: 23, 期号: 9, 页码: 45
作者:
Rustem, Abdurepqet
;
Lu, Guo-Liang
;
Liu, Jin-Zhong
;
Zhu, Chun-Hua
;
Zhang, Yu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/11/14
stars: early-type
stars: chemically peculiar
stars: magnetic field
catalogs
DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Wu, Chun-mei
;
Mao, Jia-wen
;
Zhu, Jin-zhi
;
Xie, Can-can
;
Yao, Jia-ying
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/10/17
dry eye disease
DZ2002
corneal angiogenesis
immunomodulatory function
NF-kappa B
ophthalmic therapy
Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9
作者:
Li, Hua-ying
;
Chen, Yi-li
;
Deng, Xiang-nan
;
Li, Huan-huan
;
Tan, Jie
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2023/10/17
cancer immunotherapy
B7-H3
PD-L1
bispecific antibodies
VHH
antibody-dependent cell-mediated cytotoxicity (ADCC)