中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [35]
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期刊论文 [52]
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2024 [3]
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Physics [1]
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Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7 (8H)-one derivatives as potent USP1 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18
作者:
Li, Hongrui
;
Liu, Ben-Jin
;
Xu, Jiahao
;
Song, Shan-Shan
;
Ba, Ruixian
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/08/22
USP1 inhibitor
Structure -activity relationships
Olaparib-resistant cell
The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 716, 页码: 12
作者:
Xuan, Yi-Fei
;
Lu, Shan
;
Ou, Ying-Jie
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/07/12
MAT2A inhibitor
METTL3 inhibitor
m6A
Combination therapy
NSCLC
Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2024, 卷号: 223, 页码: 17
作者:
Zhang, Qian
;
Wu, Qian
;
Huan, Xia-Juan
;
Song, Shan -Shan
;
Bao, Xu-Bin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/06/27
BET inhibitor
NAE inhibitor
BIM
Apoptosis
Combination therapy
Proteasome inhibitors reduce CD73 expression partly
via
decreasing p-ERK in NSCLC cells
期刊论文
OAI收割
LIFE SCIENCES, 2023, 卷号: 332, 页码: 10
作者:
Su, Ai-Ling
;
Tian, Chang-Qing
;
Ou, Ying-Jie
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/12/08
CD73
Proteasome inhibitors
ERK
NSCLC
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non-Small Cell Lung Cancer Cells
期刊论文
OAI收割
MOLECULAR CANCER RESEARCH, 2022, 卷号: 20, 期号: 12, 页码: 1785-1798
作者:
Sun, Lin
;
Wu, Qian
;
Huan, Xia-Juan
;
Tian, Chang-Qing
;
Wang, Ying-Qing
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/03/21
Absorption, distribution, metabolism, and excretion of [C-14]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2022, 页码: 12
作者:
Li, Xin-mei
;
Zheng, Yuan-dong
;
Zhang, Yi-fan
;
Huan, Xia-juan
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/12/13
[C-14]Mefuparib
Mefuparib (CVL218)
Blood-brain barrier
Mass balance
Tissue distribution
GastroPlus simulation
SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy
期刊论文
OAI收割
NEOPLASIA, 2022, 卷号: 32, 页码: 12
作者:
Zhou, Li-Na
;
Xiong, Chaodong
;
Cheng, Yong-Jun
;
Song, Shan-Shan
;
Bao, Xu-Bin
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/04/10
SOMCL-19-133
NAE inhibitor
MLN4924
NEDD8
Oral administration
JUNO physics and detector
期刊论文
OAI收割
PROGRESS IN PARTICLE AND NUCLEAR PHYSICS, 2022, 卷号: 123, 页码: 51
作者:
Abusleme, Angel
;
Adam, Thomas
;
Ahmad, Shakeel
;
Ahmed, Rizwan
;
Aiello, Sebastiano
  |  
收藏
  |  
浏览/下载:131/0
  |  
提交时间:2022/04/11
JUNO
neutrino physics
neutrino detector
Radioactivity control strategy for the JUNO detector
期刊论文
OAI收割
JOURNAL OF HIGH ENERGY PHYSICS, 2021, 期号: 11, 页码: 39
作者:
Abusleme, Angel
;
Adam, Thomas
;
Ahmad, Shakeel
;
Ahmed, Rizwan
;
Aiello, Sebastiano
  |  
收藏
  |  
浏览/下载:138/0
  |  
提交时间:2022/01/07
Neutrino Detectors and Telescopes (experiments)