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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [3]
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OAI收割 [3]
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Rational Design and Synthesis of Novel Benzimidazole Derivatives as Potential
β
-Glucosidase Inhibitors
期刊论文
OAI收割
LETTERS IN DRUG DESIGN & DISCOVERY, 2024, 卷号: 21, 期号: 13, 页码: 2674-2683
作者:
Liu, Xu
;
Sun, Ge
;
Li, Fengxing
;
Feng, Xia
;
Jia, Tongguan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/11/05
beta-glucosidase inhibitors
benzimidazole
linker
solvent-exposed region
o-trihydroxyphenol
iminosugar
Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14
作者:
Guo, Siqi
;
Jia, Tongguan
;
Xu, Xiaoming
;
Yang, Feng
;
Xiao, Senhao
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/04/10
ENL Inhibitor
YEATS domain
Histone lysine acetylation
Benzimidazole derivatives
Acute myeloid leukemia
Design and synthesis of novel benzimidazole-iminosugars linked a substituted phenyl group and their inhibitory activities against beta-glucosidase
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 127, 页码: 6
作者:
Liu, Xu
;
Li, Fengxin
;
Su, Lulu
;
Wang, Mingchen
;
Jia, Tongguan
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2022/08/30
Benzimidazole-iminosugars
Glucosidase inhibitors
Suzuki coupling reaction
Inhibition type
Solvent-exposed region