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浏览/检索结果: 共284条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Discovery and optimization of Menin-MLL inhibitors targeting acute myeloid leukemia 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 307, 页码: 15 作者:  Xiao, Qitao;  Wang, Yuxian;  Shen, Zheyuan;  Mo, Jun;  Li, Cong   |  收藏  |  浏览/下载：0/0  |  提交时间：2026/04/01 MLL-R AML  Menin inhibitor  thieno[2  d ]pyrimidine  Machine learning   Geochemical evidence for the potential extinction mechanisms of the floating fern Azolla in the early Eocene Arctic 期刊论文  OAI收割 GLOBAL AND PLANETARY CHANGE, 2026, 卷号: 257, 页码: 8 作者:  Fan, Xiaojie;  Zhang, Jingyu;  Nan, Jingbo;  Qin, Zhanjie;  Teng, Xiaohua   |  收藏  |  浏览/下载：0/0  |  提交时间：2026/01/20 Azolla  Arctic Ocean  Salinity  Nutrients supply  Eocene   Rational engineering of degradation tail-driven CELMoD-antibody conjugates for precision malignancy therapy 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 12, 页码: 6510-6528 作者:  Guo, Yu;  Song, Yi;  Wang, Hanlin   |  收藏  |  浏览/下载：0/0  |  提交时间：2026/01/29 Degrader-antibody conjugate  Antibody-drug conjugate  Cereblon E3 ligase modulator  Immunomodulatory drug  Molecular glue  Targeted protein degradation  Multiple myeloma  Hematologic malignancy   Evaluating the sediment control and transport of cascade check dams at Guanmenzi Gully, Beichuan County, China 期刊论文  OAI收割 JOURNAL OF MOUNTAIN SCIENCE, 2025, 卷号: 22, 期号: 11, 页码: 4052-4071 作者:  Huang, Diwen;  You, Yong;  Sun, Hao;  Liu, Daochuan;  Wang, Dongwei   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/12/23 Cascade check dams  Storage capacity  Sediment transport  DEMs of Difference (DoD)   Modular PROTAC/IMiD Bifunctional Molecule Design for the Degradation of Synergistic Targets in the Treatment of Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 20, 页码: 21249-21281 作者:  Jin, Yuheng;  Liao, Xueyan;  Zhang, Jingyu;  Duan, Haiting;  Xu, Ran   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/12/04 Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML) 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17 作者:  Mo, Jun;  Wang, Yuxian;  Pan, Youlu;  Xiao, Qitao;  Zhao, Jinyi   |  收藏  |  浏览/下载：37/0  |  提交时间：2025/08/20 Menin  High binding affinity  Anti-proliferation activity  AML   Discovery of a Selective and Potent BCL6 PROTAC with Efficacious Antiproliferative Activity for the Treatment of Diffuse Large B-Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 19, 页码: 20180-20206 作者:  Yu, Xiaoli;  Liao, Xueyan;  Zhang, Jingyu;  Wang, Hanlin;  Li, Xian   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/12/04 Boron isotope evidence for Ordovician-Silurian Transition postglacial marginal marine salinity with implications for redox conditions and biotic recovery 期刊论文  OAI收割 CHEMICAL GEOLOGY, 2025, 卷号: 690, 页码: 12 作者:  Zhang, Jingyu;  Wei, Wei;  Shen, Jun;  Nan, Jingbo;  Zhong, Yi   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/29 Boron isotopes  Marine anoxia  Mass extinction  Ordovician-Silurian transition  Yangtze Sea   The Overview and Trial Observations of AIMS 期刊论文  OAI收割 RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7 作者:  Deng, Yuanyong;  Wang, Dongguang;  Hua, Jianwen;  Xu, Songbo;  Liang, Ming   |  收藏  |  浏览/下载：71/0  |  提交时间：2025/07/14 Sun: infrared  methods: observational  instrumentation: spectrographs   Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679 作者:  Jin, Yuheng;  Qi, Xuxin;  Yu, Xiaoli;  Cheng, Xirui;  Chen, Boya   |  收藏  |  浏览/下载：46/0  |  提交时间：2025/06/23 HDAC7  PROTAC  Selectivity  Hematologic malignancies  Non-enzymatic function