机构

• 上海药物研究所 [34]
• 上海硅酸盐研究所 [4]
• 海洋研究所 [2]
• 南京地理与湖泊研究所 [1]
• 半导体研究所 [1]

采集方式

• OAI收割 [41]
• iSwitch采集 [1]

内容类型

• 期刊论文 [42]

发表日期

• 2025 [1]
• 2024 [4]
• 2022 [1]
• 2021 [1]
• 2020 [1]
• 2018 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共42条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapy 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 22 作者:  Bai, Wenjing;  Xu, Jinxin;  Gu, Wenbin;  Wang, Danyang;  Cui, Ying   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/04/01 Discovery of KW0113 as a First and Effective PROTAC Degrader of DNMT1 Protein 期刊论文  OAI收割 CHEMMEDCHEM, 2024, 页码: 16 作者:  Wang, Huihui;  Wang, Zhaoliang;  Hu, Linghao;  Yang, Bingjie;  Zong, Liangyi   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/12/16 Degrader  DNMT1  DNA methylation  PROTAC   Development of a First-in-Class DNMT1/HDAC Inhibitor with Improved Therapeutic Potential and Potentiated Antitumor Immunity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 18, 页码: 16480-16504 作者:  Chang, Yingjie;  Guo, Huahui;  Li, Xue;  Zong, Liangyi;  Wei, Jiale   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/10/21 Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase 期刊论文  OAI收割 ACS CHEMICAL BIOLOGY, 2024, 页码: 12 作者:  Zhang, Huimin;  Xu, Dounan;  Huang, Hongchan;  Jiang, Hao;  Hu, Linghao   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/05/07 PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma 期刊论文  OAI收割 CANCER RESEARCH, 2024, 卷号: 84, 期号: 3, 页码: 419-433 作者:  Tao, Hongru;  Jin, Chen;  Zhou, Liyuan;  Deng, Zhenzhong;  Li, Xiao   |  收藏  |  浏览/下载：37/0  |  提交时间：2024/04/09 Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555 作者:  Li, Ennian;  Wang, Kai;  Zhang, Bei;  Guo, Siqi;  Xiao, Senhao   |  收藏  |  浏览/下载：59/0  |  提交时间：2022/08/16 DNMT1 inhibitor  A549 cell lines  HCT116 cell lines  antitumor activity  pharmacokinetic   Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207 作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens   |  收藏  |  浏览/下载：96/0  |  提交时间：2021/08/17 Retention of nitrogen and phosphorus in Lake Chaohu, China: implications for eutrophication management 期刊论文  OAI收割 ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2020, 卷号: 27, 期号: 33, 页码: 41488-41502 作者:  Wang, Yanping;  Kong, Xiangzhen;  Peng, Zhaoliang;  Zhang, Hui;  Liu, Gang   |  收藏  |  浏览/下载：32/0  |  提交时间：2021/11/15 Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1 期刊论文  OAI收割 ACS CHEMICAL BIOLOGY, 2018, 卷号: 13, 期号: 3, 页码: 772-781 作者:  Ye, Fei;  Kong, Xiangqian;  Zhang, Hao;  Liu, Yan;  Shao, Zhiyuan   |  收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08 developmentofahighthroughputfluorescencepolarizationassayforthediscoveryofezh2eedinteractioninhibitors 期刊论文  OAI收割 actapharmacologicasinica, 2018, 卷号: 39, 期号: 2, 页码: 302 作者:  Zhu Maorong;  Du Daohai;  Hu Junchi;  Li Lianchun;  Liu Jingqiu   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 PRC2  EZH2  EED  protein-protein interaction  fluorescence polarization  high-throughput screening  apomorphine hydrochloride  oxyphenbutazone  nifedipine  ergonovine maleate