中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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近代物理研究所 [28]
上海药物研究所 [26]
武汉物理与数学研究... [19]
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期刊论文 [233]
会议论文 [9]
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2025 [2]
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Self-Oxygenating PROTAC Microneedle for Spatiotemporally-Confined Protein Degradation and Enhanced Glioblastoma Therapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2025, 页码: 13
作者:
Jiang, Xingyu
;
Lai, Yi
;
Xia, Wenzheng
;
Yang, Wenfang
;
Wang, Junjue
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/04/24
acid-activatable photodynamic therapy
double-layered microneedle
glioblastoma therapy
light-activatable PROTAC prodrug
protein degradation
Discovery of Covalent and Cell-Active ALKBH5 Inhibitors with Potent Antileukemia Effects
In Vivo
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 9
作者:
Wu, Hengbo
;
Lai, Gan-Qiang
;
Cheng, Ruixiang
;
Huang, Hui
;
Wang, Ju
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
RNA epigenetics
N
(6)-methyladenosine
ALKBH5
covalent inhibitor
antileukemia
Tumor-specific delivery of clickable inhibitor for PD-L1 degradation and mitigating resistance of radioimmunotherapy
期刊论文
OAI收割
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 46, 页码: 17
作者:
Hou, Bo
;
Ye, Jiayi
;
Huang, Lujia
;
Cheng, Wenhao
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/12/16
Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 17
作者:
Zhang, Tao
;
Pan, Zilu
;
Gao, Jing
;
Wu, Qingqing
;
Bai, Gang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/10/21
Brain responses to self- and other- unfairness under resource distribution context: Meta-analysis of fMRI studies
期刊论文
OAI收割
NEUROIMAGE, 2024, 卷号: 297, 页码: 16
作者:
Li, Qi
;
Lai, Xinyu
;
Li, Ting
;
Madsen, Kristoffer Hougaard
;
Xiao, Jing
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/08/12
Fmri
Meta -analysis
Unfairness
Self and other
Evaluation and response
Two-stage deep neural network for diagnosing fungal keratitis via in vivo confocal microscopy images
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2024, 卷号: 14, 期号: 1, 页码: 11
作者:
Li, Chun-Peng
;
Dai, Weiwei
;
Xiao, Yun-Peng
;
Qi, Mengying
;
Zhang, Ling-Xiao
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/12/06
Fungal keratitis
Image classification
Neural network
Transformer
A region-confined PROTAC nanoplatform for spatiotemporally tunable protein degradation and enhanced cancer therapy
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 18
作者:
Gao, Jing
;
Jiang, Xingyu
;
Lei, Shumin
;
Cheng, Wenhao
;
Lai, Yi
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/09/26
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
A covalent compound selectively inhibits RNA demethylase ALKBH5 rather than FTO
期刊论文
OAI收割
RSC CHEMICAL BIOLOGY, 2024, 卷号: 5, 期号: 4, 页码: 335-343
作者:
Lai, Gan-Qiang
;
Li, Yali
;
Zhu, Heping
;
Zhang, Tao
;
Gao, Jing
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/04
有毒中药
吴茱萸
吴茱萸碱
吴茱萸次碱
减毒配伍
PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 12
作者:
Zhang, Shunan
;
Lai, Yi
;
Pan, Jiaxing
;
Saeed, Madiha
;
Li, Shiqin
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2024/04/09
active tumor targeting
nanosensitizer
PROTAC prodrug
radiation therapy
tumor microenvironment