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Palladium(II)-Catalyzed Tandem γ-C(sp
2
)-H Arylation and Cyclization for the Construction of Natural Product-Like Polycyclic Fused
ortho
-Quinone Scaffolds
期刊论文
OAI收割
ORGANIC LETTERS, 2024, 页码: 6
作者:
Li, Xingjun
;
Chen, Yu
;
Xie, Xiong
;
Li, Jing
;
Wang, Jiang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/22
Ent-labdane-type diterpene glycosides obtained from
Rubus
chingii
Hu and their inhibitory effects on PDE5A activity
期刊论文
OAI收割
FITOTERAPIA, 2024, 卷号: 173, 页码: 14
作者:
Yu, Jun-dong
;
Wang, Jing-Yi
;
Liu, Jia-yuan
;
Xu, Ye-chun
;
Zhang, Xue
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/02/27
diterpene glycosides
Rubus Chingii Hu
PDE5A inhibitory activity
ent-labdane
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1
H
)-one Analogues as Potent TRK Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:
Xu, Zichao
;
Peng, Xia
;
Zhang, Renjie
;
Ji, Yinchun
;
You, Mengke
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/02/27
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model
期刊论文
OAI收割
CELL, 2023, 卷号: 186, 期号: 24, 页码: 5394-+
作者:
Chen, Yefei
;
Hong, Zexuan
;
Wang, Jingyi
;
Liu, Kunlin
;
Liu, Jing
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Natural ilmenite reference material for trace elemental in situ microanalysis
期刊论文
OAI收割
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY, 2023, 卷号: 209, 页码: 7
作者:
Luo, Yang
;
Wang, Jing
;
Xiao, Yan
;
Li, Wen-Jun
;
Wang, Shi-Ying
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/27
Ilmenite
Reference material
EMPA
LA-ICP-MS
A Phase-resolved View of the Low-frequency Quasiperiodic Oscillations from the Black Hole Binary MAXI J1820+070
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2023, 卷号: 957, 期号: 2
作者:
Shui, Qing C.
;
Zhang, S.
;
Zhang, Shuang N.
;
Chen, Yu P.
;
Kong, Ling D.
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/29
An intelligent workflow for sub-nanoscale 3D reconstruction of intact synapses from serial section electron tomography
期刊论文
OAI收割
BMC BIOLOGY, 2023, 卷号: 21, 期号: 1, 页码: 14
作者:
Chang, Sheng
;
Li, Linlin
;
Hong, Bei
;
Liu, Jing
;
Xu, Yuxuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/11/16
Serial section electron tomography
3D EM
Semi-auto locating
Auto-alignment
Missing-information restoration
Semi-auto segmentation
Workflow
Synapse
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARa nucleus-cytoplasm shuttling
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18
作者:
Zhong, Jing
;
He, Xiaofang
;
Gao, Xinxin
;
Liu, Qiaohong
;
Zhao, Yu
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/08