中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
地理科学与资源研究所 [2]
物理研究所 [1]
植物研究所 [1]
古脊椎动物与古人类研... [1]
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OAI收割 [15]
内容类型
期刊论文 [15]
发表日期
2025 [1]
2024 [2]
2023 [3]
2021 [2]
2020 [3]
2019 [1]
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学科主题
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A new species of
Urva
(Herpestidae, Carnivora) from late Upper Pleistocene deposits of East Fissure-Fillings, Fanchang, Anhui Province of Eastern China
期刊论文
OAI收割
JOURNAL OF VERTEBRATE PALEONTOLOGY, 2025, 页码: 7
作者:
Jiangzuo, Qigao
;
Wang, Yuan
;
Wang, Fazhi
;
Li, Peiran
;
Guo, Dingge
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/09/03
Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 17
作者:
Zhang, Tao
;
Pan, Zilu
;
Gao, Jing
;
Wu, Qingqing
;
Bai, Gang
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2024/10/21
A Novel IRAK4 Inhibitor DW18134 Ameliorates Peritonitis and Inflammatory Bowel Disease
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 8, 页码: 17
作者:
Huang, Yuqing
;
Ning, Yi
;
Chen, Zhiwei
;
Song, Peiran
;
Tang, Haotian
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2024/05/31
IRAK4 inhibitor
peritonitis
inflammatory bowel disease (IBD)
macrophage
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Design, Synthesis, and Evaluation of (R)-8-((Tetrahydrofuran-2-yl)methyl)pyrido[2,3-d]pyrimidin-7-ones as Novel Selective ACK1 Inhibitors to Combat Acquired Resistance to the Third-Generation EGFR Inhibitor
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17
作者:
Li, Qian
;
Zhang, Tao
;
Song, Peiran
;
Tong, Linjiang
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2023/10/17
Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:161/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
OAI收割
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:138/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
OAI收割
Molecular Cancer, 2021, 卷号: 20, 期号: 1
作者:
Zhang,Tao
;
Qu,Rong
;
Chan,Shingpan
;
Lai,Mengzhen
;
Tong,Linjiang
  |  
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2021/11/04
Spatial pattern and developing mechanism of railway geo-systems based on track gauge: A case study of Eurasia
期刊论文
OAI收割
JOURNAL OF GEOGRAPHICAL SCIENCES, 2020, 卷号: 30, 期号: 8, 页码: 1283-1306
作者:
Wang, Chengjin
;
Li, Xumao
;
Chen, Peiran
;
Xie, Yongshun
;
Liu, Weidong
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/03/18
railway
railway geosystem
development mechanism
expansion mode
Spatial pattern and developing mechanism of railway geo-systems based on track gauge: A case study of Eurasia
期刊论文
OAI收割
JOURNAL OF GEOGRAPHICAL SCIENCES, 2020, 卷号: 30, 期号: 8, 页码: 1283-1306
作者:
Wang, Chengjin
;
Li, Xumao
;
Chen, Peiran
;
Xie, Yongshun
;
Liu, Weidong
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/03/18
railway
railway geosystem
development mechanism
expansion mode