中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共849条,第1-10条 帮助

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Structural Optimization of Next-Generation TRK Inhibitors against Acquired Drug Resistance Mutations for the Treatment of Solid Tumors 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 11, 页码: 11484-11501
作者:  
Xu, Zichao;  Liu, Yueling;  Wang, Peng;  Peng, Xia;  Cheng, Jiawei
  |  收藏  |  浏览/下载:2/0  |  提交时间:2025/08/20
The combination of BET and METTL3 inhibitors elicits synergistic antitumor effects in ovarian cancer cells via reducing SP1 and BCL-2 expression 期刊论文  OAI收割
LIFE SCIENCES, 2025, 卷号: 368, 页码: 14
作者:  
Ou, Ying-Jie;  Liu, Ben-Jin;  Xuan, Yi-Fei;  Bao, Xu-Bin;  Huan, Xia-Juan
  |  收藏  |  浏览/下载:15/0  |  提交时间:2025/04/24
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:  
Tang, Cai-ling;  Li, Yuan-qing;  Du, Xi-kun;  Fang, Xiao-xia;  Guang, Yi-man
  |  收藏  |  浏览/下载:33/0  |  提交时间:2025/04/01
Probabilistic assessment of the thermal performance of low-enthalpy geothermal system under impact of spatially correlated heterogeneity by using XGBoost algorithms 期刊论文  OAI收割
ENERGY, 2024, 卷号: 313, 页码: 18
作者:  
Liao, Jianxing;  Xie, Yachen;  Zhao, Pengfei;  Xia, Kaiwen;  Xu, Bin
  |  收藏  |  浏览/下载:7/0  |  提交时间:2025/06/27
Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7 (8H)-one derivatives as potent USP1 inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18
作者:  
Li, Hongrui;  Liu, Ben-Jin;  Xu, Jiahao;  Song, Shan-Shan;  Ba, Ruixian
  |  收藏  |  浏览/下载:35/0  |  提交时间:2024/08/22
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder 期刊论文  OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:  
Zhu, Jiajia;  Chen, Xiao;  Lu, Bin;  Li, Xue-Ying;  Wang, Zi-Han
  |  收藏  |  浏览/下载:43/0  |  提交时间:2024/09/10
FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15
作者:  
Wen, Ying-quan;  Zou, Zi-yuan;  Zhao, Guan-guan;  Zhang, Meng-jiao;  Zhang, Yong-xin
  |  收藏  |  浏览/下载:31/0  |  提交时间:2024/08/22
Mineralization process of the Changjiang uranium orefield in South China: Constraints from pitchblende geochemistry 期刊论文  OAI收割
ORE GEOLOGY REVIEWS, 2024, 卷号: 169, 页码: 17
作者:  
Qi, Jia-Ming;  Xia, Xiao-Ping;  Qiu, Liang;  Liu, Bin;  Ling, Hong -Fei
  |  收藏  |  浏览/下载:53/0  |  提交时间:2024/09/13
Cross-ancestry genome-wide association studies of brain imaging phenotypes 期刊论文  OAI收割
NATURE GENETICS, 2024, 页码: 31
作者:  
Fu, Jilian;  Zhang, Quan;  Wang, Jianhua;  Wang, Meiyun;  Zhang, Bing
  |  收藏  |  浏览/下载:56/0  |  提交时间:2024/06/29
SRY-Box transcription factor 9 triggers YAP nuclear entry via direct interaction in tumors 期刊论文  OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 13
作者:  
Qian, Hui;  Ding, Chen-Hong;  Liu, Fang;  Chen, Shi-Jie;  Huang, Chen-Kai
  |  收藏  |  浏览/下载:39/0  |  提交时间:2024/05/22