中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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BMAL1/PGC1a4-FNDC5/irisin axis impacts distinct outcomes of time-of-day resistance exercise
期刊论文
OAI收割
JOURNAL OF SPORT AND HEALTH SCIENCE, 2025, 卷号: 14, 页码: 23
作者:
Guo, Mingwei
;
Shen, Fei
;
Guo, Xiaozhen
;
Zhang, Jun
;
Ma, Ying
  |  
收藏
  |  
浏览/下载:109/0
  |  
提交时间:2025/04/01
Daily variance
Circadian
Muscle strength
Metabolic benefits
Resistance exercise
Design and structural optimization of novel SOS1 inhibitors in KRAS-driven cancers
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 125, 页码: 8
作者:
Chen, Yating
;
Liu, Qiupei
;
Meng, Xianghui
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
SOS1 inhibitor
KRAS mutation
SOS1-KRAS interaction
Resistance
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
A CMTM6 Nanobody Overcomes EGFR-TKI Resistance in Non-Small Cell Lung Cancer
期刊论文
OAI收割
ADVANCED SCIENCE, 2025, 卷号: 12, 期号: 27, 页码: 17
作者:
Xia, Lu
;
Wang, Jichuan
;
Xue, Hui
;
Li, Haimeng
;
Li, Qinghua
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
CMTM6
EGFR
EGFR-TKIs resistance
NSCLC
nanobody
Shifting sands to sustainable soils: Spatial dynamics of soil water and salinity in a desert oasis ecotone
期刊论文
OAI收割
AGRICULTURAL WATER MANAGEMENT, 2025, 卷号: 316, 页码: 109562
作者:
Cao, Qiqi
;
Liu, Tao
;
Xia, Jiangbao
;
Li, Junran
;
Ravi, Sujith
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/07/18
Bare sand dunes
Nabkha dunes
Long-term cultivation
Soil water-salt dynamics
Deep soil profiles
Secondary salinization risk
A new specific GluN2B partial antagonist ameliorates brain injury caused by ischemic stroke in rats
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 161, 页码: 15
作者:
Fan, Yanhua
;
Wu, Hongshan
;
Yin, Dan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/07/25
FLY26
GluN2B partial antagonists
Ischemic stroke
BDNF/TrkB signaling pathway
A post-common-envelope binary with double-peaked Balmer emission lines from TMTS
期刊论文
OAI收割
Astronomy and Astrophysics, 2025, 卷号: 698
作者:
Liu, Qichun
;
Wang, Xiaofeng
;
Lin, Jie
;
Wu CY(吴程远)
;
Li, Chunqian
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/06/10
techniques: radial velocities
binaries: spectroscopic
stars: evolution
white dwarfs
stars: winds
outflows
Strategic Amino Acid Mutations in CPD Cleavage Motif: Impacts on Hydrolysis and C-Terminal Modification Efficiency
期刊论文
OAI收割
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2025, 卷号: 41, 期号: 3, 页码: 592-600
作者:
Yashinov, Ansor
;
Zou, Xiangman
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/06/23
Protein engineering
C-Terminal modification
Cysteine protease domain
Self-cleavage tag
AlphaFold2
Structural Optimization of Next-Generation TRK Inhibitors against Acquired Drug Resistance Mutations for the Treatment of Solid Tumors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 11, 页码: 11484-11501
作者:
Xu, Zichao
;
Liu, Yueling
;
Wang, Peng
;
Peng, Xia
;
Cheng, Jiawei
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Development of 3-arylaminothiophenic-2-carboxylic acid derivatives as new FTO inhibitors showing potent antileukemia activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 17
作者:
Zhang, Deyan
;
Liu, Lu
;
Li, Ming
;
Hu, Xinyi
;
Zhang, Xi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/24
RNA modification
N 6-methyladenosine
Demethylase FTO
Structure-activity relationship
Antileukemia