机构

• 上海药物研究所 [7]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2006 [2]
• 2005 [1]
• 2004 [2]
• 2003 [2]

学科主题

• Pharmacolo... [1]

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3 '-substituted tyrosine derivatives 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2006, 卷号: 49, 期号: 5, 页码: 1585-1596 作者:  Song, YL;  Peach, ML;  Roller, PP;  Qiu, S;  Wang, SM   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 Binding affinity difference induced by the stereochemistry of the sulfoxide bridge of the cyclic peptide inhibitors of Grb2-SH2 domain: NMR studies for the structural origin 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2005, 卷号: 330, 期号: 4, 页码: 1254-1261 作者:  Shi, YH;  Song, YL;  Lin, DH;  Tan, JZ;  Roller, PP   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 solution structure  NMR  dynamics  Grb2-SH2 domain inhibitors  cyclic peptide  signal transduction  chiral sulfoxide  configuration   Synthesis and HIV-1 integrase inhibitory activity of dimeric and tetrameric analogs of indolicidin 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 卷号: 14, 期号: 22, 页码: 5595-5598 作者:  Krajewski, K;  Marchand, C;  Long, YQ;  Pommier, Y;  Roller, PP   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 indolicidin  integrase inhibitors  multimeric peptides   Development of L-3-aminotyrosine suitably protected for the synthesis of a novel nonphosphorylated hexapeptide with low-nanomolar Grb2-SH2 domain-binding affinity 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 卷号: 14, 期号: 12, 页码: 3205-3208 作者:  Song, YL;  Roller, PP;  Long, YQ   |  收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 aminotyrosine  Grb2-SH2 domain  nonphosphorylated ligand  cyclic peptide  sulfoxide  SPR assay   Potentiating effect of distant sites in non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 卷号: 310, 期号: 2, 页码: 334-340 作者:  Long, YQ;  Guo, RB;  Luo, JH;  Yang, DJ;  Roller, PP   |  收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 non-phosphorylated Grb2-SH2 antagonist  thioether-bridged cyclic peptide  hydrophobic residue  sulfoxide linkage  conformational constraint  phage library  global optimization  chemotherapeutic agents  intracellular signaling  ErbB2-related cancer   Global optimization of conformational constraint on non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2003, 卷号: 11, 期号: 18, 页码: 3929-3936 作者:  Long, YQ;  Lung, FDT;  Roller, PP   |  收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08