中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
金属研究所 [58]
上海药物研究所 [18]
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OAI收割 [100]
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期刊论文 [98]
CNKI期刊论文 [1]
会议论文 [1]
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Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel
Hs
ClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:
Sun, Mingyang
;
Chen, Beijing
;
Teng, Dan
;
Zhao, Hongshen
;
Liao, Yilie
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
Prediction of Solvate Based on Graph Attention Network
期刊论文
OAI收割
CRYSTAL GROWTH & DESIGN, 2025, 卷号: 25, 期号: 2, 页码: 297-308
作者:
Sun, Shihui
;
Wang, Jian-Rong
;
Tang, Lei
;
Fan, Zhehuan
;
Li, Xutong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Chen, Beijing
;
Sun, Mingyang
;
Zhang, Chun
;
Huang, Qi
;
Teng, Dan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/12/25
Sodium oligomannate disrupts the adherence of Rib
high
bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 19
作者:
Wang, Xinyi
;
Xie, Zuoquan
;
Yuan, Jie
;
Jin, Enjing
;
Lian, Wen
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/12/16
Prediction of Multi-Pharmacokinetics Property in Multi-Species: Bayesian Neural Network Stacking Model with Uncertainty
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2024, 页码: 16
作者:
Zhang, Yuanyuan
;
Xie, Zhiyin
;
Xiao, Fu
;
Yu, Jie
;
Fan, Zhehuan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/11
pharmacokinetic parameters
machine learning
uncertainty
stacking
multitask learning
ADME
3D Noncontact Micro-Particle Manipulation With Acoustic Robot End-Effector Under Microscope
期刊论文
OAI收割
IEEE ROBOTICS AND AUTOMATION LETTERS, 2024, 卷号: 9, 期号: 9, 页码: 7979-7986
作者:
Wang, Mingyue
;
Li, Jiaqi
;
Jia, Yuyu
;
Sun, Zhenhuan
;
Su, Hu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/09/09
Acoustics
End effectors
Three-dimensional displays
Robot kinematics
Impedance
Phased arrays
Acoustic field
micro/nano robotics
microscopic vision
noncontact particle manipulation
In silico off-target profiling for enhanced drug safety assessment
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 2927-2941
作者:
Liu, Jin
;
Gui, Yike
;
Rao, Jingxin
;
Sun, Jingjing
;
Wang, Gang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/08/22
Drug safety
Off-target prediction
Adverse drug reactions
Toxicity
Molecular representation
Artificial intelligence
Vision-Based Closed-Loop Control With Spatiotemporal Multiplexing Strategy for Noncontact Trapping of Multiple Micro-Particles
期刊论文
OAI收割
IEEE TRANSACTIONS ON AUTOMATION SCIENCE AND ENGINEERING, 2024, 页码: 13
作者:
Wang, Mingyue
;
Li, Jiaqi
;
Zhong, Chengxi
;
Li, Teng
;
Sun, Zhenhuan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/07/22
Acoustics
Robots
Robot kinematics
Echo sounders
Microscopy
End effectors
Needles
Noncontact robot manipulation
automated particle trapping
phased transducer array
microscopic vision
KinomeMETA: a web platform for kinome-wide polypharmacology profiling with meta-learning
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2024, 页码: 9
作者:
Li, Zhaojun
;
Qu, Ning
;
Zhou, Jingyi
;
Sun, Jingjing
;
Ren, Qun
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/06/27
Potential source and health risks of black carbon based on MERRA-2 reanalysis data in a typical industrial city of North China Plain
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL MANAGEMENT, 2024, 卷号: 354, 页码: 8
作者:
Yu, Hao
;
Li, Menghui
;
Zheng, Xueqing
;
Zhu, Mingyue
;
Zheng, Zhensen
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/09/12
MERRA-2
BC
Potential source
Health risk