中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [28]
自动化研究所 [7]
西北高原生物研究所 [4]
合肥物质科学研究院 [4]
广州地球化学研究所 [2]
深圳先进技术研究院 [1]
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OAI收割 [49]
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期刊论文 [46]
会议论文 [3]
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2024 [3]
2023 [2]
2022 [4]
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2019 [4]
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纳米科技与材料物理:... [2]
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Design, Synthesis, and Biological Evaluation of Novel Diaminopyrimidine Macrocycles as Fourth Generation Reversible EGFR Inhibitors That Overcome Clinical Resistance to Osimertinib Mediated by C797S Mutation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 22, 页码: 20531-20558
作者:
Hu, Shiliang
;
Tong, Linjiang
;
Qin, Qiao
;
Wen, Jiaxin
;
Li, Yan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/11
Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 17
作者:
Zhang, Tao
;
Pan, Zilu
;
Gao, Jing
;
Wu, Qingqing
;
Bai, Gang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/10/21
Comprehensive Attribute Prediction Learning for Person Search by Language
期刊论文
OAI收割
IEEE TRANSACTIONS ON IMAGE PROCESSING, 2024, 卷号: 33, 页码: 1990-2003
作者:
Niu, Kai
;
Huang, Linjiang
;
Long, Yuzhou
;
Huang, Yan
;
Wang, Liang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/07/03
Person search by language
cross-modal retrieval
smart video surveillance
attribute prediction
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Improving Inconspicuous Attributes Modeling for Person Search by Language
期刊论文
OAI收割
IEEE TRANSACTIONS ON IMAGE PROCESSING, 2023, 卷号: 32, 页码: 3429-3441
作者:
Niu, Kai
;
Huang, Tao
;
Huang, Linjiang
;
Wang, Liang
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/11/17
Person search by language
cross-modal retrieval
smart video surveillance
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 11, 页码: 7697-7716
作者:
Zhang, Shurui
;
Chen, Xiaoxu
;
Wu, Chenglin
;
Xu, Hui
;
Xie, Xiong
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/16
SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 21
作者:
Wang, Xiaomin
;
Chen, Ziqi
;
Xu, Jun
;
Tang, Shuai
;
An, Nan
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2022/06/15
Discovery of N-(3-bromo-1H-indol-5-yl)-quinazolin-4-amine as an effective molecular skeleton to develop reversible/irreversible pan-HER inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 233, 页码: 13
作者:
Tang, Qidong
;
Peng, Ting
;
Hu, Jie
;
Zhang, Tao
;
Chen, Pengqin
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/08/16
Reversible
irreversible pan-HER inhibitor
Quinazolin-4-amine derivatives
Anti-tumor
Structure-activity relationship
Multi-Modality Self-Distillation for Weakly Supervised Temporal Action Localization
期刊论文
OAI收割
IEEE TRANSACTIONS ON IMAGE PROCESSING, 2022, 卷号: 31, 页码: 1504-1519
作者:
Huang, Linjiang
;
Wang, Liang
;
Li, Hongsheng
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/03/17
Location awareness
Reliability
Noise measurement
Annotations
Training
Head
Task analysis
Weakly supervised temporal action localization
multi-modality
pseudo label
self-distillation
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
OAI收割
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:110/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance