中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [22]
武汉岩土力学研究所 [12]
地理科学与资源研究... [11]
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期刊论文 [161]
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Pharmacokinetics, mass balance, and metabolism of [
14
C]PLB1004, a selective and irreversible EGFR-TKI in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 14
作者:
Liu, Donghui
;
Li, Qian
;
Yan, Shu
;
Zhang, Xinyue
;
Li, Weiqiang
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
PLB1004
[C-14]PLB1004
Radioactivity
Mass balance
EGFR-TKI
Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel
Hs
ClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:
Sun, Mingyang
;
Chen, Beijing
;
Teng, Dan
;
Zhao, Hongshen
;
Liao, Yilie
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
PEGylation of Dipeptide Linker Improves Therapeutic Index and Pharmacokinetics of Antibody-Drug Conjugates
期刊论文
OAI收割
BIOCONJUGATE CHEMISTRY, 2025, 页码: 11
作者:
Long, Jing
;
Shao, Ting
;
Wang, Yongmei
;
Chen, Tianzhi
;
Chen, Yuning
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
Supply risk propagation in international trade networks of the tungsten industry chain
期刊论文
OAI收割
HUMANITIES & SOCIAL SCIENCES COMMUNICATIONS, 2025, 卷号: 12, 期号: 1, 页码: 16
作者:
Zheng, Xinxin
;
Li, Huajiao
;
Liu, Xiaojie
;
Wang, Xingxing
;
Zhang, Yuqi
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/03/31
Simultaneous Quantification of Total Antibody and Conjugated Payload for DS001 in Rat Serum Using a Hybrid Immuno-Capture LC-MS/MS
期刊论文
OAI收割
AAPS JOURNAL, 2025, 卷号: 27, 期号: 1, 页码: 13
作者:
Yu, Xiong
;
Li, Weiqiang
;
Huang, Wensi
;
Xiao, Bo
;
Long, Jing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
ADC
LC-MS/MS
payload
simultaneous quantification
total antibody
Utility of quantitative whole-body autoradiography (QWBA) and oxidative combustion (OC) analysis in the assessment of tissue distribution of [
14
C]Mefuparib (CVL218) in SD and LE rats
期刊论文
OAI收割
PLOS ONE, 2024, 卷号: 19, 期号: 12, 页码: 13
作者:
Li, Xinmei
;
Wang, Feiyu
;
Zhang, Xinyue
;
Shen, Xiaokun
;
Yang, Chunhao
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/04/01
Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:
Nie, Hui-Jun
;
Li, Ben-Fu
;
Sun, Jingya
;
Yuan, Yali
;
Zhang, Zhi-Gao
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/26
Triple-negative breast cancer
Targeting transcription regulation
Orally bioavailable degrader
PROTAC
Cyclin-dependent Kinase 9
Physical mechanism-based simulation methods for soil and ground heat flux from observations at multi-sites
期刊论文
OAI收割
JOURNAL OF HYDROLOGY, 2024, 卷号: 645, 页码: 132168
作者:
Liu, Zhaofei
;
Jiang, Dong
;
Wang, Rui
;
Hao, Mengmeng
;
Zhang, Xingxing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/20
Ground heat flux
Soil heat flux
Simulation
Gradient method
Calorimetry method
Triple collocation
Tibetan Plateau
Sculpting Mechanical Properties of Hydrogels by Patterning Seamlessly Interlocked Stiff Skeleton
期刊论文
OAI收割
Advanced Functional Materials, 2024, 卷号: 34, 期号: /, 页码: 2417477
作者:
Bin, Zhu
;
Jiayu, Wu
;
Desheng, Liu
;
Yuke, Yan
;
Xingxing, Yang
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/12/13
The advance of ultrasound-enabled diagnostics and therapeutics
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2024, 卷号: 375, 页码: 1-19
作者:
Han, Biying
;
Liu, Yan
;
Zhou, Qianqian
;
Yu, Yuting
;
Liu, Xingxing
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/01/14
Ultrasonic medicine
Sonosensitizer
Sonodynamic therapy
Cavitation effect
Deep penetration