中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [23]
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期刊论文 [156]
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Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10
作者:
Zhang, Chun
;
Yan, Xue
;
Gao, Li-Xin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
Imidazo[2,1-b][1,3,4]thiadiazole
Inhibitory activities
Fluorescence imaging
Zebrafish
SHP2
Guiding precision medicine strategy for intravenous ginsenosides via pharmacokinetic-informed bioinformatic approaches: a study on XueShuanTong
期刊论文
OAI收割
PHYTOMEDICINE, 2025, 卷号: 143, 页码: 18
作者:
Jia, Wei-Wei
;
Tian, Nan-Nan
;
Song, Zi-Jing
;
Lan, Xiao-Fang
;
Yang, Xi-He
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Precision medicine
Physiologically based pharmacokinetic model
Ginsenoside
Albumin-facilitated dissociation
Drug interaction
Drug transporter
Hepatic impairment
Bright Bursts with Submillisecond Structures of FRB 20230607A in a Highly Magnetized Environment
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 1
作者:
Zhou, DeJiang
;
Han, J. L.
;
Zhang, Bing
;
Zhu, WeiWei
;
Wang, Wei-yang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/07/28
PRL-3: unveiling a new horizon in cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 11
作者:
Cao, Zi-tong
;
Mao, Jia-luo
;
Huang, Chang-ying
;
Wang, Han-lin
;
Wang, Ming-zhi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/06/23
Phosphatase of Regenerating Liver-3 (PRL3)
tumor metastasis
targeted therapies
PRL-3-zumab
Synthesis, fluorescence properties of novel thiazolo[3,2-b][1,2,4]triazol derivatives as potent SHP2 inhibitors and its uses in sensing for Fe3+and cell imaging
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1324, 页码: 12
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Gan, Su-Ya
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2025/01/14
Thiazolo[3,2-b][1,2,4]triazole
Salicylic acid
Fe3+ion
Fluorescence property
SHP2
Novel functionalized benzimidazole-salicylic acid derivatives: synthesis, photophysical characteristics and biological applications
期刊论文
OAI收割
JOURNAL OF MATERIALS CHEMISTRY B, 2025, 页码: 11
作者:
Yan, Xue
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Gan, Su-Ya
;
Fu, Yi-Qiu
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2025/04/01
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2025/04/01
Circulating metabolites of
Borneolum syntheticum
(Bingpian) ameliorate atherosclerosis in ApoE
-/-
mice via inhibiting macrophage foam-cell formation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 18
作者:
He, Rong-rong
;
Ma, Chuan-rui
;
He, Xin
;
Dong, Yan-xi
;
Li, Hui
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/11/26
Borneolum syntheticum
Bingpian
borneol
isoborneol
metabolism
atherosclerosis
19
F qNMR based pharmacokinetics, metabolism and mass balance studies of SARS-CoV-2-3CL protease inhibitor simnotrelvir (SIM0417) in humans
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Wang, Ze-yu
;
Ren, Yong-mei
;
Hu, Shu-wei
;
Zhang, Nai-xia
;
Dong, Meng-xiao
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/11/05
COVID-19
simnotrelvir
F-19 qNMR
pharmacokinetics
metabolism
mass balance.
Heterozygous variants in USP25 cause genetic generalized epilepsy
期刊论文
OAI收割
BRAIN, 2024, 页码: 16
作者:
Fan, Cui-Xia
;
Liu, Xiao-Rong
;
Mei, Dao-Qi
;
Li, Bing-Mei
;
Li, Wen-Bin
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/10/09
genetic generalized epilepsy
USP25
gain of function
loss of function