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Chinese Academy of Sciences Institutional Repositories Grid
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Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Design and synthesis of CDK9/EZH2 dual-target inhibitors to achieve synergistic antitumor effects
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 14
作者:
Tian, Lina
;
Xiao, Jian
;
Zeng, Yanping
;
Li, Yangsha
;
Wei, Aihuan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
CDK9
EZH2
Dual target inhibitor
DLBCL
First polarization study of the M87 jet and active galactic nuclei at submillimeter wavelengths with ALMA
期刊论文
OAI收割
ASTRONOMY & ASTROPHYSICS, 2025, 卷号: 699
作者:
Goddi, Ciriaco
;
Carlos, Douglas F.
;
Crew, Geoffrey B.
;
Matthews, Lynn D.
;
Messias, Hugo
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/08/25
black hole physics
magnetic fields
polarization
radiation mechanisms: non-thermal
instrumentation: interferometers
instrumentation: polarimeters
Long-circulating enzyme-activated HSP90-targeted camptothecin derivatives
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2025, 卷号: 383, 页码: 16
作者:
Ding, Mengyuan
;
Shen, Qianqian
;
Su, Yi
;
Lu, Yingxin
;
Jin, Jiyu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/07/25
eHSP90
Camptothecin derivatives
Cathepsin B
Long-circulating
The Overview and Trial Observations of AIMS
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7
作者:
Deng, Yuanyong
;
Wang, Dongguang
;
Hua, Jianwen
;
Xu, Songbo
;
Liang, Ming
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/07/14
Sun: infrared
methods: observational
instrumentation: spectrographs
The patterns of the Populus euphratica forest and cropland changes upstream of the Tarim River under the policy-driven human activities during 1960-2023
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF REMOTE SENSING, 2025, 卷号: N/A
作者:
Wang, Haoyu
;
Li, Junli
;
Ke, Yingming
;
Zhang, Yihan
;
Zhou, Chenghu
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/07/18
Cropland
P. euphratica forest
spatio-temporal changes
remote sensing
policy-driven human activities
Methotrexate exerts antitumor immune activity and improves the clinical efficacy of immunotherapy in patients with solid tumors
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2025, 卷号: 17, 期号: 801, 页码: 18
作者:
Yang, Ruirui
;
Wang, Bei
;
Su, Zhaoming
;
Song, Ying
;
Zhang, Yingying
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
A Unified Strategy for Transition-Metal-Free Synthesis of Benzothienopyridines, Benzoselenopyridines, and Benzotelluropyridines and Related Analogues
期刊论文
OAI收割
ORGANIC LETTERS, 2025, 卷号: 27, 期号: 23, 页码: 6047-6053
作者:
Wen, Zhaoyue
;
Wu, Jianlian
;
Wang, Chun
;
Shen, Bingjie
;
Fu, Mingyue
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Comparative transcriptomic analysis reveals a differential acid response mechanism between estuarine oyster (Crassostrea ariakensis) and Pacific oyster (Crassostrea gigas)
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2025, 卷号: 297, 页码: 12
作者:
Wang, Shen-Tong
;
Yang, Qi
;
Liu, Ming-Kun
;
Li, Li
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/07/11
Front-loading
Ion channel
Ocean and coastal acidification
Oyster
Resilience
Translational control
Design and Development of a Novel Oral 4′-Fluorouridine Double Prodrug VV261 against SFTSV
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 9, 页码: 9811-9826
作者:
Cheng, Yong
;
Zheng, Wei
;
Dong, Xinru
;
Sun, Tengxiao
;
Xu, Mengwei
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/06/23