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Therapeutic potential and pharmacological mechanisms of Traditional Chinese Medicine in gout treatment
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 21
作者:
Guo, Jing-wen
;
Lin, Guo-qiang
;
Tang, Xin-yi
;
Yao, Jia-ying
;
Feng, Chen-guo
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
gout
hyperuricemia
gouty arthritis
Traditional Chinese Medicine
TCM formula
Chinese herb
Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 19
作者:
Yin, Wen
;
Xu, Heng
;
Bai, Zhonghao
;
Wu, Yue
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
A Self-Assembled Nano-Molecular Glue (Nano-mGlu) Enables GSH/H
2
O
2
-Triggered Targeted Protein Degradation in Cancer Therapy
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 卷号: 147, 期号: 1, 页码: 372-383
作者:
Sun, Jie
;
Gu, Mingxi
;
Peng, Lvyang
;
Guo, Jing
;
Chen, Peng
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/04/01
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
PM
2.5
-mediated cardiovascular disease in aging: Cardiometabolic risks, molecular mechanisms and potential interventions
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 954, 页码: 22
作者:
Chanda, Francis
;
Lin, Kai-xuan
;
Chaurembo, Abdallah Iddy
;
Huang, Jian-yuan
;
Zhang, Hui-juan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/11/05
PM2.5
Cardiovascular disease
Cardiometabolic risk
Older adults
Inflammation
Oxidative stress
Oxidative stress
Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:
Nie, Hui-Jun
;
Li, Ben-Fu
;
Sun, Jingya
;
Yuan, Yali
;
Zhang, Zhi-Gao
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/26
Triple-negative breast cancer
Targeting transcription regulation
Orally bioavailable degrader
PROTAC
Cyclin-dependent Kinase 9
GRB 240529A: A Tale of Two Shocks
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2024, 卷号: 976, 期号: 2
作者:
Sun, Tian-Rui
;
Geng, Jin-Jun
;
Yan, Jing-Zhi
;
Hu, You-Dong
;
Wu, Xue-Feng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/12/02
Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2024/12/25
colchicine
MLN4924
multi-omics analysis
phosphoproteomics
ubiquitinomics
kinase inhibitor
Sodium oligomannate disrupts the adherence of Rib
high
bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 19
作者:
Wang, Xinyi
;
Xie, Zuoquan
;
Yuan, Jie
;
Jin, Enjing
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/12/16
Rubidium isotopes reveal dehydration and melting of the subducting slab beneath the Mariana arc
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2024, 卷号: 646, 页码: 13
作者:
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/10/21
Rb isotopes
Subduction zones
Mariana arc
AOC dehydration
Sediment partial melting