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From Hit to Lead: Discovery of First-In-Class Furanone Glycoside D228 Derived from
Chimonanthus salicifolius
for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 19, 页码: 17101-17123
作者:
Tang, Mei-Lin
;
Xiong, Xiao-Yu
;
Zhang, Heyanhao
;
Wang, Yun-Zhi
;
Cheng, Rong-Qian
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/10/21
Heterozygous variants in USP25 cause genetic generalized epilepsy
期刊论文
OAI收割
BRAIN, 2024, 页码: 16
作者:
Fan, Cui-Xia
;
Liu, Xiao-Rong
;
Mei, Dao-Qi
;
Li, Bing-Mei
;
Li, Wen-Bin
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/10/09
genetic generalized epilepsy
USP25
gain of function
loss of function
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/09/10
Positive benefit-risk ratio of Psoraleae Fructus: Comprehensive safety assessment and osteogenic effects in rats
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 326, 页码: 13
作者:
Shi, Zhuo
;
Pan, Jin-chao
;
Ru, Yi
;
Shen, Ning-ning
;
Liu, Yu-fu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/05/31
Psoraleae fructus
Osteogenic effects
Toxicology
Long-term administration
Liver injury
Magmatic-hydrothermal evolution of the Koktokay No. 3 pegmatite, Altai, northwestern China: Constraints from in situ boron isotope and chemical compositions of tourmaline
期刊论文
OAI收割
LITHOS, 2023, 卷号: 462, 页码: 17
作者:
Yin, Rong
;
Huang, Xiao-Long
;
Wang, Ru-Cheng
;
Wei, Gang-Jian
;
Xu, Yi-Gang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/09/14
Tourmaline
Boron isotopes
Fractional crystallization
Hydrothermal fluid
Rare-metal mineralization
LCT-type pegmatite
Zircons in NYF-type pegmatites in the Emeishan large igneous province, SW China: A record of Nb and REE mineralization processes
期刊论文
OAI收割
ORE GEOLOGY REVIEWS, 2023, 卷号: 162, 页码: 15
作者:
Yin, Rong
;
Sun, Xiao-Ming
;
Wang, Sheng-Wei
;
Wang, Ru-Cheng
;
Ran, Meng-Lan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/09/12
NFY-pegmatite
Zircon
Nb-REE mineralization
Magmatic-hydrothermal evolution
Mantle plume
Ligand recognition and G protein coupling of the human itch receptor MRGPRX1
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 12
作者:
Guo, Lulu
;
Zhang, Yumu
;
Fang, Guoxing
;
Tie, Lu
;
Zhuang, Yuming
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2024/01/16
Design of Ni(OH)2 nano-boxes@CuS nanosheets hollow hierarchical structure to achieve synergistic catalysis for high sensitivity dopamine electrochemical sensing
期刊论文
OAI收割
JOURNAL OF ALLOYS AND COMPOUNDS, 2022, 卷号: 929, 页码: 8
作者:
Liu, Yumiao
;
Liu, Yurong
;
Ou, Hanwen
;
Shi, Dongping
;
Tian, Liangliang
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/02/24
Ni(OH)2 nano-boxes
CuS nanosheets
Hollow hierarchical structure
Coordinated etching and precipitation
Dopamine electrochemical sensor
A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1 beta and IL-6
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4180-4192
作者:
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2023/04/10
Glycolysis
Phosphoglycerate kinase 1
Macrophages
NRF2
Inflammation
Cocrystal Prediction of Bexarotene by Graph Convolution Network and Bioavailability Improvement
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 10, 页码: 19
作者:
Xiao, Fu
;
Cheng, Yinxiang
;
Wang, Jian-Rong
;
Wang, Dingyan
;
Zhang, Yuanyuan
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/12/13
bexarotene
cocrystal prediction
GCN
bioavailability