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Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [54]
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Nutrient addition alters drought resistance and resilience via forb abundance in a temperate grassland
期刊论文
OAI收割
AGRICULTURE ECOSYSTEMS & ENVIRONMENT, 2025, 卷号: 380, 页码: 8
作者:
Luo, Dengnan
;
Yang, Guojiao
;
Zhang, Guangru
;
Liu, Qianguang
;
Guo, Qun
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/02/06
Resistance
Resilience
Grassland
Drought
Nitrogen addition
Phosphorus addition
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Solvent-Controlled Divergent Cyclization of 3-Ylideneoxindoles with Ethyl 2-Diazoacetate: Access to Spirocyclopropyl and Spiropyrazolines Oxindoles
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2024, 页码: 7
作者:
Xie, Ding-Xiong
;
Huang, Yue-Mei
;
Lin, Xiao-Ming
;
Kang, Zheng-Hui
;
Ni, Chen-Chen
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/12/11
Spirocyclopropyl oxindole
Spiropyrazoline oxindole
Catalyst-free
Solvent-controlled
3-Ylideneoxindole
V1bR enhances glucose-stimulated insulin secretion by paracrine production of glucagon which activates GLP-1 receptor
期刊论文
OAI收割
CELL AND BIOSCIENCE, 2024, 卷号: 14, 期号: 1, 页码: 11
作者:
Yun, Ying
;
Guo, Shimeng
;
Xie, Xin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/10/21
Arginine vasopressin
Insulin
Glucagon
V1bR
GLP-1R
Islets
Diabetes
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/09/10
Structural basis of tethered agonism and G protein coupling of protease-activated receptors
期刊论文
OAI收割
CELL RESEARCH, 2024, 页码: 10
作者:
Guo, Jia
;
Zhou, Yun-Li
;
Yang, Yixin
;
Guo, Shimeng
;
You, Erli
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/08/22
Topoisomerase Inhibitors and PIM1 Kinase Inhibitors Improve Gene Editing Efficiency Mediated by CRISPR-Cas9 and Homology-Directed Repair
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 12, 页码: 12
作者:
Yun, Ying
;
Wang, Min
;
Guo, Shimeng
;
Xie, Xin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/22
CRISPR-CAS9
gene editing
homology-directed repair
knock-in
A novel approach to exploit Small-Molecule glucagon-like Peptide-1 receptor agonists with high potency
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 107, 页码: 19
作者:
Wang, Xiaoyan
;
Yun, Ying
;
Chen, Lili
;
Guo, Shimeng
;
Niu, Buying
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/07/12
Diabetes
GLP-1 receptor
Agonist
Structural optimization
Water molecule replacement
Structure activity relationship
Docking simulation
Discovery of an Ortho-Substituted
N
-Cyclopropylmethyl-7α-phenyl-6,14-
endo
ethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 9, 页码: 7112-7129
作者:
Li, Zixiang
;
Ye, Rufeng
;
He, Qian
;
Lu, Jiashuo
;
Sun, Yanting
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/06/27
A Novel IRAK4 Inhibitor DW18134 Ameliorates Peritonitis and Inflammatory Bowel Disease
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 8, 页码: 17
作者:
Huang, Yuqing
;
Ning, Yi
;
Chen, Zhiwei
;
Song, Peiran
;
Tang, Haotian
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/05/31
IRAK4 inhibitor
peritonitis
inflammatory bowel disease (IBD)
macrophage