机构

• 上海药物研究所 [22]
• 化学研究所 [8]
• 重庆绿色智能技术研究... [5]
• 地质与地球物理研究所 [4]
• 水生生物研究所 [4]
• 昆明植物研究所 [4]
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采集方式

• OAI收割 [81]
• iSwitch采集 [3]

内容类型

• 期刊论文 [81]
• 会议论文 [3]

发表日期

• 2025 [4]
• 2024 [3]
• 2023 [1]
• 2022 [15]
• 2021 [12]
• 2020 [7]
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学科主题

• Chemistry,... [2]
• Astronomy ... [1]
• Biochemist... [1]
• Chemistry,... [1]
• Pharmacolo... [1]
• Plant Scie... [1]
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浏览/检索结果: 共84条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Fluorescence-Coupled Ubiquitination Assay as a High-Throughput Screening Strategy for Novel Cereblon Degraders 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 10111-10127 作者:  Deng, Yanan;  Yang, Shiling;  Xu, Hesong;  Ding, Xiyao;  Xu, Ying   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/06/23 Structure-Based Discovery of a Series of Novel MAT2a Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2025, 页码: 5 作者:  Zhou, Yushan;  Wang, Li;  Ren, Ruyue;  Zhang, Junjie;  Huan, Xiajuan   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/05/27 MAT2a  MTAP  Synthetic lethality  Allosteric inhibitor  Structure-activity relationship   Multisite modifications of arenes using ketones as removable handles enabled by Pd and norbornene cooperative catalysis 期刊论文  OAI收割 NATURE SYNTHESIS, 2025, 卷号: 4, 期号: 2 作者:  Tao, Kai-Liang;  Wang, Xing;  Liu, Huan;  Chen, Wen-Qing;  Sun, Yi   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/06/04 Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16 作者:  Tang, Cai-ling;  Li, Yuan-qing;  Du, Xi-kun;  Fang, Xiao-xia;  Guang, Yi-man   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/04/01 dynamics simulation  CECR2  covalent inhibitor  allosteric effect   FAPM: functional annotation of proteins using multimodal models beyond structural modeling 期刊论文  OAI收割 BIOINFORMATICS, 2024, 卷号: 40, 期号: 12, 页码: 12 作者:  Xiang, Wenkai;  Xiong, Zhaoping;  Chen, Huan;  Xiong, Jiacheng;  Zhang, Wei   |  收藏  |  浏览/下载：100/0  |  提交时间：2025/01/14 Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7 (8H)-one derivatives as potent USP1 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18 作者:  Li, Hongrui;  Liu, Ben-Jin;  Xu, Jiahao;  Song, Shan-Shan;  Ba, Ruixian   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/08/22 USP1 inhibitor  Structure -activity relationships  Olaparib-resistant cell   Rethinking Polyp Segmentation from An Out-of distribution Perspective 期刊论文  OAI收割 Machine Intelligence Research, 2024, 卷号: 21, 期号: 4, 页码: 631-639 作者:  Ge-Peng Ji;  Jing Zhang;  Dylan Campbell;  Huan Xiong;  Nick Barnes   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/07/18 Polyp segmentation  anomaly segmentation  out-of-distribution segmentation  masked autoencoder  abdomen   E3 ligase ligand optimization of Clinical PROTACs 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2023, 卷号: 11, 页码: 15 作者:  Jiang, Hanrui;  Xiong, Huan;  Gu, Shuang-Xi;  Wang, Mingliang   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/04/10 PROTACs  E3 ubiquitin ligase ligand  structure optimization  clinical trials  CRBN   Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540 作者:  Xie, Xiong;  Zheng, Yu-Gui;  Chen, Huan;  Li, Jian;  Luo, Rong-Hua   |  收藏  |  浏览/下载：38/0  |  提交时间：2023/04/10 Exploring the impact of mass migration in Jin Dynasty by psycholinguistic analysis on Classical Chinese legacy text 期刊论文  OAI收割 FRONTIERS IN PSYCHOLOGY, 2022, 卷号: 13, 页码: 8 作者:  Xiong, Huan;  Wu, Gengxuan;  Li, Sijia;  Xue, Shujie;  Li, Hua   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/01/06 psycholinguistic analysis  word frequency analysis  LIWC  Classical Chinese legacy text  mass migration  gentry of the Jin Dynasty