机构

• 上海药物研究所 [18]
• 上海硅酸盐研究所 [3]
• 工程热物理研究所 [3]
• 过程工程研究所 [2]
• 大连化学物理研究所 [1]
• 光电技术研究所 [1]
• 更多

采集方式

• OAI收割 [28]

内容类型

• 期刊论文 [22]
• 会议论文 [6]

发表日期

• 2025 [2]
• 2024 [1]
• 2023 [2]
• 2019 [2]
• 2018 [2]
• 2017 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共28条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文  OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19 作者:  Yao, Mingyue;  Yan, Wenzhong;  Wang, Yafang;  Zhao, Yu;  Xu, Xiaowei   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/04/01 Acute myeloid leukemia  HDAC inhibitor  FLT3-ITD mutation  DNA damage response  Synergistic effect  Drug resistance   Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia 期刊论文  OAI收割 CANCER RESEARCH, 2025, 卷号: 85, 期号: 1, 页码: 101-117 作者:  Luo, Ziwei;  Lin, Chencen;  Yu, Chuwei   |  收藏  |  浏览/下载：12/0  |  提交时间：2025/02/28 Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS-mutant Cancers 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 20 作者:  Wang, Yafang;  Xu, Lansong;  Ling, Lijun;  Yao, Mingyue;  Shi, Shangxuan   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/10/21 KRAS  CDK9  ERK  complement activation  immunosuppression   Targeting ST8SIA6-AS1 counteracts KRASG12C inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling 期刊论文  OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22 作者:  Wang, Yafang;  Yao, Mingyue;  Li, Cheng;  Yang, Kexin;  Qin, Xiaolong   |  收藏  |  浏览/下载：28/0  |  提交时间：2024/01/26 KRAS(G12C)  c-Myc  PLK1  LncRNA  ST8SIA6-AS1  Drug resistance   Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15 作者:  Mei, Lianghe;  Xu, Lansong;  Wu, Sanan;  Wang, Yafang;  Xu, Chao   |  收藏  |  浏览/下载：60/0  |  提交时间：2023/10/17 Betulinic acid  ROR & gamma  Target identification  Rationale structure optimization  Anti-tumor effects  antagonists   Oxygen defect engineering in cobalt iron oxide nanosheets for promoted overall water splitting 期刊论文  OAI收割 JOURNAL OF MATERIALS CHEMISTRY A, 2019, 卷号: 7, 期号: 38, 页码: 21704-21710 作者:  Guo, Chengying;  Liu, Xuejing;  Gao, Lingfeng;  Ma, Xiaojing;  Zhao, Mingzhu   |  收藏  |  浏览/下载：90/0  |  提交时间：2019/12/02 Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N-terminal Inhibitors Without Induction of Heat Shock Response 期刊论文  OAI收割 CHEMISTRYOPEN, 2019, 卷号: 8, 期号: 3, 页码: 344-353 作者:  Liu, Peng;  Chen, Xiangling;  Zhu, Jianming;  Li, Bo;  Chen, Zhaoqiang   |  收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01 autophagy  Hsp72  Hsp90 inhibitor  triazines  antitumor activity   Combined inhibition of PI3K delta and FLT3 signaling exerts synergistic antitumor activity and overcomes acquired drug resistance in FLT3-activated acute myeloid leukemia 期刊论文  OAI收割 CANCER LETTERS, 2018, 卷号: 420, 页码: 49-59 作者:  He, Ye;  Sun, Liping;  Xu, Yongping;  Fu, Li;  Li, Yun   |  收藏  |  浏览/下载：48/0  |  提交时间：2019/01/08 Acute myeloid leukemia  FLT3  PI3K delta  CAL101  Synergistic effect   pharmacokineticsanddispositionofanlotinibanoraltyrosinekinaseinhibitorinexperimentalanimalspecies 期刊论文  OAI收割 actapharmacologicasinica, 2018, 卷号: 039, 期号: 006, 页码: 1048 作者:  Zhong Chenchun;  Chen Feng;  Yang Junling;  Jia Weiwei;  Li Li   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 酷氨酸  布置  动物种类  试验性  血浆蛋白质  相互作用  新陈代谢  CYP3A   Puquitinib, a novel orally available PI3K inhibitor, exhibits potent antitumor efficacy against acute myeloid leukemia 期刊论文  OAI收割 CANCER SCIENCE, 2017, 卷号: 108, 期号: 7, 页码: 1476-1484 作者:  Xie, Chengying;  He, Ye;  Zhen, Mingyue;  Wang, Yulan;  Xu, Yongping   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 Acute myeloid leukemia  CAL-101  PI3K signaling  PI3K  puquitinib