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Chinese Academy of Sciences Institutional Repositories Grid
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BMAL1/PGC1a4-FNDC5/irisin axis impacts distinct outcomes of time-of-day resistance exercise
期刊论文
OAI收割
JOURNAL OF SPORT AND HEALTH SCIENCE, 2025, 卷号: 14, 页码: 23
作者:
Guo, Mingwei
;
Shen, Fei
;
Guo, Xiaozhen
;
Zhang, Jun
;
Ma, Ying
  |  
收藏
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浏览/下载:82/0
  |  
提交时间:2025/04/01
Daily variance
Circadian
Muscle strength
Metabolic benefits
Resistance exercise
Design, synthesis, and activity evaluation of indole derivatives as potential stabilizers for p53 Y220C
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 121, 页码: 9
作者:
Li, Linquan
;
Gu, Xi
;
Meng, Jingyi
;
Wen, Yiming
;
Yi, Jing
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收藏
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浏览/下载:0/0
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提交时间:2025/05/27
p53 Y220C
Synthesis
Structural modification
Drug design
Microbiota-shaped neutrophil senescence regulates sexual dimorphism in bladder cancer
期刊论文
OAI收割
NATURE IMMUNOLOGY, 2025, 卷号: 26, 期号: 5, 页码: 46
作者:
Zhu, Qingchen
;
Zhang, Guiheng
;
Cao, Ming
;
Huang, Huan
;
He, Dan
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收藏
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浏览/下载:0/0
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提交时间:2025/06/23
Glabridin as a selective Kv2.1 inhibitor ameliorates DPN pathology by disrupting the Aβ/Kv2.1/JNK/NF-κB/NLRP3/p-Tau pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 17
作者:
Xu, Jia-wen
;
Ma, Lin
;
Xiang, Yu
;
Dai, Meng-qing
;
Li, Qiu-hui
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/05/27
diabetic peripheral neuropathy
glabridin
Kv2.1
dorsal root ganglia
Schwann cells
A beta/Kv2.1/NLRP3/p-Tau axis
A prominent oxygenation event in the late Mesoproterozoic broke the calm of the second half of the "Boring Billion"
期刊论文
OAI收割
PALAEOGEOGRAPHY PALAEOCLIMATOLOGY PALAEOECOLOGY, 2025, 卷号: 662, 页码: 13
作者:
Meng, Lin
;
Shi, Xiaoying
;
Zhou, Limin
;
Li, Jie
;
Liu, Wei
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/04/03
Ce anomaly
Mo isotope
Taizi Formation
Yemahe Formation
South China
I/(Ca plus Mg)
Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13
作者:
Wu, Feifei
;
Li, Huiyu
;
Li, Weiqiang
;
Zhang, Laishun
;
An, Qi
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收藏
  |  
浏览/下载:8/0
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提交时间:2025/04/01
Optimization
Hematopoietic progenitor kinase 1
Inhibitor
Cancer immunotherapy
Design, Synthesis, and Pharmacological Evaluation of Quinazoline and Quinoline Derivatives as Potent ENPP1 Inhibitors for Cancer Immunotherapy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 18
作者:
He, Jie
;
Ma, Xiaoyu
;
Sun, Jia
;
Chen, Manman
;
Xu, Lan
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收藏
  |  
浏览/下载:9/0
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提交时间:2025/04/01
Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Temporal shifts in dengue epidemic in Guangdong Province before and during the COVID-19 pandemic: a Bayesian model study from 2012 to 2022
期刊论文
OAI收割
PLOS NEGLECTED TROPICAL DISEASES, 2025, 卷号: 19, 期号: 2, 页码: e0012832
作者:
Xu, Jiaqing
;
Tan, Xiaohua
;
Quan, Yi
;
Gong, Dexin
;
Deng, Hui
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/03/18
Mantle induced hydration and oxidation of intracontinental granite sources in the North China Craton
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2025, 卷号: 651, 页码: 9
作者:
Yang, Chuan-Mao
;
Xu, Yi-Gang
;
Xia, Xiao-Ping
;
Yang, Jin-Hui
;
Huang, Xiao-Long
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/04/01
Intracontinental granite
Zircon water content
Oxygen fugacity
North China Craton
Mantle-derived melts/fluids