中国科学院机构知识库网格
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Pharmacokinetics, mass balance, and metabolism of [
14
C]PLB1004, a selective and irreversible EGFR-TKI in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 14
作者:
Liu, Donghui
;
Li, Qian
;
Yan, Shu
;
Zhang, Xinyue
;
Li, Weiqiang
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2025/04/01
PLB1004
[C-14]PLB1004
Radioactivity
Mass balance
EGFR-TKI
Pharmacokinetics, mass balance, and metabolism of [
14
C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 12
作者:
Gao, Lei
;
Ma, Sheng
;
Yan, Shu
;
Zhang, Hua
;
Tian, Ling
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/07/25
FCN-437c
CDK4/6 inhibitor
Mass balance
Radiopharmacokinetics
Drug metabolism
Qualitative and quantitative determination of SIPI-2011 and its two major metabolites in human plasma
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 264, 页码: 11
作者:
Fang, Jie
;
Jing, Jiao
;
Li, Guangyao
;
Wang, Yongbin
;
Zhao, Binjiang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SIPI-2011
UPLC-UV/Q-TOF
LC-MS/MS
Metabolic Profiling
Pharmacokinetics
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
The Chinese Pulsar Timing Array Data Release I Single pulsar noise analysis
期刊论文
OAI收割
ASTRONOMY & ASTROPHYSICS, 2025, 卷号: 699
作者:
Chen, Siyuan
;
Xu, Heng
;
Guo, Yanjun
;
Wang, Bojun
;
Caballero, R. Nicolas
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/07/21
gravitational waves
methods: data analysis
pulsars: general
Deep Learning With ERA5 Variables Accurately Simulates Near-Surface Wind Speed Variations Across a Complex Terrain Region
期刊论文
OAI收割
GEOPHYSICAL RESEARCH LETTERS, 2025, 卷号: 52, 期号: 12, 页码: e2025GL116108
作者:
Long, Zhiyi
;
Zha, Jinlin
;
Zhang, Hao
;
Chuan, Ting
;
Lu, Wenxi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/07/18
wind speed
deep learning
complex terrain region
Tibetan Plateau
transformer
convolutional neural networks
Ultrabright ratiometric Raman-guided epilepsy surgery by intraoperatively visualizing proinflammatory microglia
期刊论文
OAI收割
CELL REPORTS MEDICINE, 2025, 卷号: 6, 期号: 6, 页码: 28
作者:
Wang, Cong
;
Li, Zhi
;
Zhu, Xiao
;
Sun, Wanbing
;
Ding, Yue
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Risk assessment of CYP3A induction by ginsenoside's metabolites from oral Panax notoginseng (sanqi) extract
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 349, 页码: 11
作者:
Deng, Yang
;
Du, Jing
;
He, Xin
;
Dong, Yan-Xi
;
Wang, Xiao-Lei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Panax notoginseng
Ginsenoside
Intestinal microbiota
CYP3A induction
Drug interaction
Discussion of "Volume Contraction and Reduction in Hydraulic Conductivity during Particle Crushing"
期刊论文
OAI收割
JOURNAL OF GEOTECHNICAL AND GEOENVIRONMENTAL ENGINEERING, 2025, 卷号: 151, 期号: 6, 页码: 3
作者:
Liu, Xinyu
;
Zhang, Xianwei
;
Yan, Lei
;
Wei, Gang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/06/27
Organic-Inorganic Fertilization Sustains Crop Yields While Mitigating N
2
O and NO Emissions in Subtropical Wheat-Maize Systems
期刊论文
OAI收割
AGRICULTURE-BASEL, 2025, 卷号: 15, 期号: 10, 页码: 21
作者:
Liu, Yan
;
Hu, Lei
;
Zhang, Shihang
;
Yao, Zhisheng
;
Zhou, Minghua
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/07/21
nitrogen use efficiency
crop residue substitution
soil nitrogen surplus
subtropical agroecosystems
revised "hole-in-the-pipe" model