机构

• 上海药物研究所 [4]
• 广州生物医药与健康研... [2]
• 深圳先进技术研究院 [1]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2023 [1]
• 2018 [2]
• 2017 [1]
• 2013 [2]
• 2012 [1]

学科主题

• Chemistry [2]

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR plus Human Prostate Cancer 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 18, 页码: 13280-13303 作者:  Xiang, Weiguo;  Zhao, Lijie;  Han, Xin;  Xu, Tianfeng;  Kregel, Steven   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/12/08 Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 15, 页码: 6685-6704 作者:  Qin, Chong;  Hu, Yang;  Zhou, Bing;  Fernandez-Salas, Ester;  Yang, Chao-Yie   |  收藏  |  浏览/下载：54/0  |  提交时间：2019/01/08 Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 14, 页码: 6110-6120 作者:  Zhao, Yujun;  Zhou, Bing;  Bai, Longchuan;  Liu, Liu;  Yang, Chao-Yie   |  收藏  |  浏览/下载：58/0  |  提交时间：2019/01/08 Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 9, 页码: 3887-3901 作者:  Zhao, Yujun;  Bai, Longchuan;  Liu, Liu;  McEachern, Donna;  Stuckey, Jeanne A.   |  收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 Pyrimido[4,5-d]pyrimidin-4(1H)-one Derivatives as Selective Inhibitors of EGFR Threonine(790) to Methionine(790) (T790M) Mutants 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 卷号: 52, 期号: 32 作者:  Zhang, Lianwen;  Ding, Ke;  Wang, Shaomeng;  Ren, Xiaomei;  Li, Honglin   |  收藏  |  浏览/下载：42/0  |  提交时间：2018/12/13 Pyrimido[4,5-d]pyrimidin-4(1H)-one Derivatives as Selective Inhibitors of EGFR Threonine(790) to Methionine(790) (T790M) Mutants 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 卷号: 52, 期号: 32 Xu, Tianfeng; Zhang, Lianwen; Xu, Shilin; Yang, Chao-Yie; Luo, Jinfeng; Ding, Fang; Lu, Xiaoyun; Liu, Yingxue; Tu, Zhengchao; Li, Shiliang; Pei, Duanqing; Cai, Qian; Li, Honglin; Ren, Xiaomei; Wang, Shaomeng; Ding, Ke 收藏  |  浏览/下载：56/0  |  提交时间：2016/12/16 Bivalent Smac mimetics with a diazabicyclic core as highly potent antagonists of XIAP and cIAP1/2 and novel anticancer agents 期刊论文  OAI收割 Journal of medicinal chemistry, 2012 作者:  Peng, Yuefeng;  Sun, Haiying;  Lu, Jianfeng;  Liu, Liu;  Cai, Qian 收藏  |  浏览/下载：20/0  |  提交时间：2015/08/25