中国科学院机构知识库网格
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Bicyclic polyprenylated acylphloroglucinol-related meroterpenoids as potent DRAK2 inhibitors from
Hypericum patulum
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 232, 页码: 10
作者:
Huang, Jin-Chang
;
Jia, Xin-Yu
;
Lv, Yi-Fan
;
Xu, Hong-Hong
;
Han, Ming
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Hypericum patulum
Hypericaceae
Meroterpenoids
Hyperpatins A-H
Death-associated protein kinase-related
apoptosis-inducing kinase 2
Glucose-stimulated insulin secretion
Synthesis, fluorescence properties of novel thiazolo[3,2-b][1,2,4]triazol derivatives as potent SHP2 inhibitors and its uses in sensing for Fe3+and cell imaging
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1324, 页码: 12
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Gan, Su-Ya
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/01/14
Thiazolo[3,2-b][1,2,4]triazole
Salicylic acid
Fe3+ion
Fluorescence property
SHP2
Novel functionalized benzimidazole-salicylic acid derivatives: synthesis, photophysical characteristics and biological applications
期刊论文
OAI收割
JOURNAL OF MATERIALS CHEMISTRY B, 2025, 页码: 11
作者:
Yan, Xue
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Gan, Su-Ya
;
Fu, Yi-Qiu
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Evaluating the performance of five global gridded potential evapotranspiration products in hydrological simulation: Application in the upper Han River Basin
期刊论文
OAI收割
JOURNAL OF HYDROLOGY-REGIONAL STUDIES, 2025, 卷号: 57, 页码: 102114
作者:
Li, Minxin
;
Zou, Lei
;
Xia, Jun
;
Cao, Hui
;
Zhang, Hairong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/02/24
Potential evapotranspiration
Spatial-temporal variation
Hydrological simulation
DTVGM
The upper Han River Basin
Benzofurans and dibenzofurans from galls on twigs of the endangered Chinese endemic tree
Parrotia
subaequalis
and their inhibitory properties against
Staphylococcus
aureus
and ATP-citrate lyase
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 229, 页码: 9
作者:
Zhou, Peng-Jun
;
Wu, Xi-Ying
;
Zhao, Ze-Yu
;
Zang, Yi
;
Sun, Zhong-Shuai
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/11/26
Parrotia subaequalis
Hamamelidaceae
Gall
Phytoalexins
Benzofuran
Dibenzofuran
Staphylococcus aureus
ATP-Citrate lyase
6
H
-Indolo-[2,3-
b
]-quinoxaline derivatives as promising bifunctional SHP1 inhibitors
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 页码: 12
作者:
Zhang, Chun
;
Dong, Yi-Xin
;
Gao, Li-Xin
;
Gan, Suya
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/02/28
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Zhai, Lin-hui
;
Jia, Xing-long
;
Chen, Yu-lu
;
Liu, Mu-yin
;
Zhang, Jing-dan
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2024/12/25
colchicine
MLN4924
multi-omics analysis
phosphoproteomics
ubiquitinomics
kinase inhibitor
Mass balance, metabolism, and pharmacokinetics of [
14
C]amdizalisib, a clinical-stage novel oral selective PI3Kδ inhibitor for the treatment of non-hodgkin's lymphoma, in healthy Chinese volunteers
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Zhao, Chun-Yang
;
Zhang, Li-Jun
;
Sun, Chan
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/01/06
amdizalisib
PI3K delta kinase
metabolism
mass balance
metabolite identification
pharmacokinetics
safety
Phytochemical and biological studies on rare and endangered plants endemic to China. Part XXXVI. Tsugaforrestiacids A - O: Structurally diverse C-18 carboxylated diterpenoids from the twigs and needles of the 'vulnerable ' conifer Tsuga forrestii and their inhibitory effects on ATP-citrate lyase
期刊论文
OAI收割
PHYTOCHEMISTRY, 2024, 卷号: 226, 页码: 13
作者:
Zhou, Peng -Jun
;
Zhao, Ze-Yu
;
Zhu, Jin-Xin
;
Zang, Yi
;
Benjamin, Menny M.
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/08/22
Tsuga forrestii
Pinaceae
Rare and endangered plants (REPs)
Diterpenoid acids
ATP citrate lyase (ACL)
Molecular docking
Chemotaxonomy